Protein Purification
Abcam FH-535, Wnt/beta-cantenin inhibitor, 10MG
MW 361.2 Da, Purity >98%. Wnt/β-cantenin inhibitor and PPARγ and PPARδ antagonist. Suppresses proliferation of cancer cells in vitro. Antitumor agent.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sivelestat, neutrophil elastase inhibitor, 25MG
MW 434.5 Da. Potent, selective, substrate competitive neutrophil elastase inhibitor (IC₅₀ values are 19-49 nM and 5.6 μM for leukocyte and pancreas elastase respectively). Suppresses neutrophil-induced capillary permeability and leukocyte kinetics. Active in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam E-64d (Alo x istatin), cathepsin B and L inhibitor, 5MG
MW 342.4 Da, Purity >98%. Irreversible cell-permeable cathepsin B and L inhibitor. Inhibits calpain. Inhibits autophagy. Inhibits platelet proteolysis. Reduces brain amyloid-β levels. Shows neuroprotective effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Hampton Research HR4-955/Mounted CryoLoop - 20 micron, 0.1 - 0.2 mm - 25 pack
HR4-955/Mounted CryoLoop - 20 micron, 0.1 - 0.2 mm - 25 pack. Please note items from this supplier are non-returnable.
Revvity Health Sciences Inc Tag-lite Adenosine A1 receptor Frozen & Labeled Cells, 200 Assay Points
Tag-lite Adenosine A1 receptor Frozen & Labeled Cells, 200 Assay Points
Revvity Health Sciences Inc Tag-lite Adenosine A2B receptor Frozen & Labeled Cells, 200 Assay Points
Tag-lite Adenosine A2B receptor Frozen & Labeled Cells, 200 Assay Points
Abcam Tetrabenazine, VMAT2 inhibitor, 5MG
MW 317.42 g/mol. Potent, reversible VMAT2 inhibitor (IC₅₀ = 3.2 nM, Ki = 100 nM). Depletes monoamines stores and decreases uptake into synaptic vesicles. Shows antihyperkinetic effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sulfobetaine 3-16, Zwitterionic detergent, 25G
MW 391.7 Da, Purity >98%. Zwitterionic detergent. Solubilizes membrane proteins. Retains zwitterionic characteristics over wide pH range.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CRT0066101 (mM/ml), protein kinase D inhibitor, 20MM_ML
MW 411.33 g/mol, Purity >99%. Potent and selective protein kinase D inhibitor (IC₅₀ values are 1, 2 and 2.5 nM at PKD1, PKD3 and PKD2, respectively). Reduces proliferation of pancreatic cancer cells. Orally active. Antitumor agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc PhenoVue Multi Organelle Staining Kit 1x384
PhenoVue Multi Organelle Staining Kit 1x384
Abcam Embelin, cell-permeable inhibitor of x -linked inhibitor of apoptosis, 50MG
MW 294.4 Da, Purity >98%. Potent, cell-permeable inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC₅₀ = 4.1 μM). Binds to the XIAP BIR3 protein and interacts with residues crucial for Smac and caspsase-9 binding. Inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells (IC₅₀ = 3.7 - 5.7 μM); minimal effects on normal prostate cells (IC₅₀ = 19.3 - 20.1 μM). Antitumor and anti-inflammatory effects in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sulfobetaine 3-16, Zwitterionic detergent, 5G
MW 391.7 Da, Purity >98%. Zwitterionic detergent. Solubilizes membrane proteins. Retains zwitterionic characteristics over wide pH range.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ML7, myosin light chain kinase inhibitor, 50MG
MW 452.7 Da, Purity >99%. Potent and selective myosin light chain kinase inhibitor (MLCK) (Ki = 300 nM). Also inhibits PKA and PKC (Ki values are 21 and 42 μM, respectively). Cell-permeable. Inhibits tumor cell growth.
The product is subject to the following: Abcam Restricted Use Statement
Abcam KU-60019, ATM kinase inhibitor, 200MG
MW 547.7 Da, Purity >98%. Potent, highly selective ATM kinase inhibitor (IC₅₀ = 6.3 nM). Inhibits migration and invasion of glioma cells. Shows similar target selectivity to KU-55933 (ab120637). Shows radiosensitizing effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement