Protein Purification
STEMCELL Technologies EasySep™ Human Pan-Granulocyte Isolation Kit, For processing: 1 x 10^9 cells
The EasySep™ Human Pan-Granulocyte Enrichment Kit is designed to isolate granulocytes (eosinophils, basophils and neutrophils) from normal peripheral whole blood by negative selection. Undesired cells are targeted for removal with Tetrameric Antibody Complexes recognizing non-granulocytes and magnetic particles. The labeled cells are separated using an EasySep™ magnet without the use of columns. Desired cells are poured off into a new tube.
STEMCELL Technologies EasySep™ Human CD8 Positive Selection Kit II, For processing: 1 x 10^9 cells
The EasySep™ Human CD8 Positive Selection Kit II is designed to isolate CD8+ cells from fresh or previously frozen peripheral blood mononuclear cells or washed leukapheresis samples by immunomagnetic positive selection. Desired cells are targeted with antibody complexes recognizing CD8 and magnetic particles. The cocktail also contains an antibody to human Fc receptor to minimize nonspecific binding. Labeled cells are separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off. The CD8 antigen is expressed on cytotoxic T cells and weakly on a subset of NK cells.This product replaces the EasySep™ Human CD8 Positive Selection Kit (Catalog #18053) for even faster cell isolations.
Abcam (-)-Nutlin-3, p53-MDM2 binding inhibitor, 10MG
MW 581.5 Da, Purity >98%. Potent p53-MDM2 binding inhibitor (IC50 = 90 nM). Enantiomer of (+)-Nutlin-3 (ab144426). Shows antiproliferative effects (IC50 values are 2.2 and 1.3 µM for human skin and murine fibroblasts respectively). Shows antitumor effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (+)-Nutlin-3, p53-MDM2 binding inhibitor, 1MG
MW 581.5 Da, Purity >98%. p53-MDM2 binding inhibitor (IC₅₀ = 13 μM). Less potent enantiomer of (-)-Nutlin-3 (Asc-4428
The product is subject to the following: Abcam Restricted Use Statement
Abcam O x amflatin, HDAC inhibitor, 5MG
MW 342.4 Da, Purity >95%. Potent mammalian HDAC inhibitor (IC₅₀ = 15.7 nM). Induces an elongated cell shape morphology with filamentous protrusions. Shows antiproliferative effects. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Btx-A51 (casein kinase inhibitor A51) | 2079068-74-7 | MFCD34469352 | 98.6% | 360.88 g·mol⁻¹ | C18H25ClN6 | 50MG
BTX-A51 is a small-molecule inhibitor of casein kinase 1α (CK1α) that also shows activity against transcriptional kinases CDK7 and CDK9. Reported as orally active, it induces apoptosis in leukemia cell models and is used in preclinical studies to investigate CK1α/CDK biology. The compound is supplied as a solid powder with high analytical purity for use in biochemical, cellular, and in vivo research.
- Potent inhibitor of casein kinase 1α and transcriptional CDKs.
- Orally active with reported anti-leukemic activity.
- Induces apoptosis in leukemia cell models.
- High purity suitable for biochemical and cellular assays.
- Supplied as a solid powder, white to light yellow.
- Available in multiple pack sizes including 50 mg.
- Molecular weight 360.88 g·mol⁻¹; formula C18H25ClN6.
- Suitable for preclinical and mechanistic studies of CK1α/CDK pathways.
Mitochondria-Targeted Montana Paintbrush Red (Red MitoPaint) Expression Kit - Big Sky BacMam, 5mL - Montana Molecular
Bright, red fluorescent mitochondrial label for live-cell imaging—no fixation, staining, or cell lysis required. Visualize mitochondrial morphology and dynamics in real time, over hours to days, in living cells. Delivered via Montana Molecular’s Big Sky BacMam vector for enhanced expression across a wide range of cell types, including primary cultures and iPSCs. Targeted to mitochondria via Cox8. Ideal for dynamic, non-destructive studies of mitochondrial organization, cellular phenotypes, and high-content imaging.
STEMCELL Technologies EasySep™ Human Monocyte Isolation Kit, For processing: 1 x 10^9 cells
The EasySep™ Human Monocyte Isolation Kit is designed to isolate CD14+CD16- monocytes from fresh or previously frozen peripheral blood mononuclear cells or washed leukapheresis samples by immunomagnetic negative selection. The EasySep™ procedure involves labeling unwanted cells and platelets with antibody complexes and magnetic particles. The magnetically labelled cells are separated from the untouched desired cells by using an EasySep™ magnet and simply pouring or pipetting the desired cells into a new tube.This product can be used in place of the EasySep™ Human Monocyte Enrichment Kit (Catalog #19059) for even faster cell isolations with reduced platelet contamination.