Protein Purification
MilliporeSigma™ Calbiochem™ InSolution™ eIF4E/eIF4G Interaction Inhibitor, 4EGI-1
A cell-permeable hydrazone compound that reversibly binds eukaryotic translation initiation factor 4E (eIF4E; KD = 25μM) and disrupts eIF4E/eIF4G, but not eIF4E/4E-BP1, complex format
MilliporeSigma™ Calbiochem™ Calpastatin Peptide
A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC50 = 20 nM for purified rabbit calpain II).
MilliporeSigma™ Calbiochem™ Calcium Entry Blocker Set, Pyr6 & Pyr10
A set of PYR6, a CRAC Channel Inhibitor III; and PYR10, a TPRC3 Channel Inhibitor III.
MilliporeSigma™ Calbiochem™ Calpain Inhibitor V
The Calpain Inhibitor V controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI
The Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI controls the biological activity of Dual Specificity Protein Phosphatase 1/6. Primarily used for Phosphorylation & Dephosphorylation apps.
MilliporeSigma™ Calbiochem™ Phenylarsine Oxide
A membrane-permeable protein tyrosine phosphatase inhibitor (IC50 = 18 μM).
MilliporeSigma™ Calbiochem™ TCPOBOP
The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents.
MilliporeSigma™ Calbiochem™ Granzyme B Inhibitor IV
The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ ATM/ATR Kinase Inhibitor
The ATM/ATR Kinase Inhibitor, also referenced under CAS 905973-89-9, controls the biological activity of ATM/ATR Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ HMTase Inhibitor IX, MM-102
A cell-permeable peptidomimetic that prevents MLL1 (Mixed Lineage Leukemia 1) from complex assembling with WDR5 (Trp-Asp Repeat Domain 5), RbBP5 (Retinoblastoma Binding Protein 5), and ASH2L (Absent Small or Homeotic-2-Like) for enhanced H3K4 methyltransferase activity (IC50
MilliporeSigma™ Calbiochem™ MIF Antagonist, ISO-1
The MIF Antagonist, ISO-1, also referenced under CAS 478336-92-4, controls the biological activity of MIF.
MilliporeSigma™ Calbiochem™ Bisindolylmaleimide I
A highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor (IC50 = 10 nM) that is structurally similar to staurosporine.
MilliporeSigma™ Calbiochem™ SB-269970 Hydrochloride
A selective 5-HT7 receptor antagon
MilliporeSigma™ Calbiochem™ DUB Inhibitor VI, P22077
The DUB Inhibitor VI, P22077 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Clioquinol
A metal ion chelator that crosses the blood brain barrier and acts as a neurotoxic antibiotic.