Protein Purification
MilliporeSigma™ Calbiochem™ MK-2 Inhibitor IV, MK-25
The MK-2 Inhibitor IV, MK-25 controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ mGlu7 Antagonist, XAP044
A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC50 = 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells).
MilliporeSigma™ Calbiochem™ Dihydroorotate Dehydrogenase Inhibitor, Brequinar
An immunosuppressive and anti-neoplastic agent that inhibits pyrimidine synthesis by blocking the activity of mammalian mitochondrial dihydroorotate dehydrogenase (DHODH; IC50 = 12 nM).
MilliporeSigma™ Calbiochem™ JNK Inhibitor I, (L)-Form, Cell-Permeable
The JNK Inhibitor I, (L)-Form, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NFAT Inhibitor, MCV1
The NFAT Inhibitor, MCV1 controls the biological activity of NFAT.
MilliporeSigma™ Calbiochem™ Caspase-9 Substrate II, Colorimetric
The Caspase-9 Substrate II, Colorimetric serves as the substrate for Caspase-9.
MilliporeSigma™ Calbiochem™ Phorbol-12-myristate-13-acetate
Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.
MilliporeSigma™ Calbiochem™ Colcemid
Cell synchronization agent.
MilliporeSigma™ Calbiochem™ Retro-2
A cell-permeable tricyclic imine compound that inhibits the endosome-to-Golgi retrograde transport, but not cellular uptake, of CtxB, StxB without affecting cellular uptake/trafficking of Tf or EGF.
MilliporeSigma™ Calbiochem™ Latrunculin A, Latrunculia magnifica
Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM).
MilliporeSigma™ Calbiochem™ AG 1478
A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase.
MilliporeSigma™ Calbiochem™ SIRT1/2/3 pan Inhibitor
A thienopyrimidinylcarboxamide that acts as a highly potent, reversible pan sirtuin (SIRT) inhibitor (IC50 = 15, 10, and 33nM for SIRT1, 2, and 3, respective
MilliporeSigma™ Calbiochem™ PknG Inhibitor
The PknG Inhibitor, also referenced under CAS 329221-38-7, controls the biological activity of PknG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Pin1 Inhibitor, DTM
A cell permeable competitive inhibitor of Pin1 (EC50 = 4.1 μM, Ki = 50 nM).