Protein Purification
Cayman Chemical MonacylglycRol LIpase InhIb 96
MAGL is the main enzyme responsible for the inactivation of 2-AG. Cayman’s Monoacylglycerol Lipase Inhibitor Screening Assay provides a convenient method for screening human MAGL inhibitors. MAGL hydrolyzes 4-nitrophenylacetate resulting in a yellow product, 4-nitrophenol, with an absorbance of 405-412 nm.
Cayman Chemical IKK2 InhIbItr VI 1mg
A potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM); used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses
Cayman Chemical Syk InhIbItr II 500ug
A cell-permeable, selective, and reversible inhibitor of Syk (IC50 = 41 nM); prevents FcεRI-mediated 5-HT release in RBL-2H3 cells in vitro (IC50 = 460 nM) and inhibits passive cutaneous anaphylaxis reactions in mice (ID50 = 13.2 mg/kg, s.c.)
CPC Scientific H-Ile-Thr-Ser-Phe-Glu-Glu-Ala-Lys-Gly-Leu-Asp-Arg-Ile-Asn-Glu-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro-OH (trifluoroacetate salt) 1MG
Amino acid sequence of this peptide that is identical with the C-terminal region of the calmodulin-bing domain. It inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 m M) using [32P] myosin light chain as a substrate but has no effect on Ni2+ -stimulated activity. ONE-LETTER SEQUENCE: ITSFEEAKGLDRINERMPPRRDAMPMOLECULAR FORMULA: C124H205N39O39S2MOLECULAR WEIGHT:2930.34STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [148067-21-4], RESEARCH AREA: Protein Kinases and PhosphatasesREFERENCES: Y. Hashimoto et al., J. Biol. Chem., 265, 1924 (1990)
CPC Scientific H-Ser-Phe-Leu-Leu-Arg-OH (trifluoroacetate salt) 5MG
The peptide is the minimal peptide length which retains full activity in releasing serotonin from human platelets.ONE-LETTER SEQUENCE: SFLLRMOLECULAR FORMULA: C30H50N8O7MOLECULAR WEIGHT:634.78STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [141685-53-2 ], SYNONYMS: Thrombin Receptor Activator Peptide 5, PAR-1 (1-5) (human), Proteinase Activated Receptor 1 (1-5) (human), Thrombin Receptor (1-5) (human), Coagulation Factor II Receptor (1-5) (human), Thrombin Receptor Activator for Peptide 5 (TRAP-5)RESEARCH AREA: HematologyREFERENCES: T.Sabo et al., Biochem. Biophys. Res. Commun., 188, 604 (1992)
Gentarget NFKB-LUC /GFP/ LENTIVIRUS IN P
Pre-made lentivirus express Firefly Luciferase 3 reporter under a minimal promoter inserted with 4 tandem repeats of NFκB transcriptional response element /NFkB-TRE/ for detecting NFkB regulated signaling pathway activity.
Medchemexpress LLC (E)-2-amino-4-methyl-5-phosphonopent-3-enoic acid | 127910-31-0 | MFCD00153906 | 98.3% | 209.14 g·mol-1 | C6H12NO5P | 1 MG
CGP 37849 is a selective, competitive N-methyl-D-aspartate (NMDA) receptor antagonist with reported oral activity. It has demonstrated anticonvulsant activity and antidepressant- and anxiolytic-like effects in rodent models, and is used in pharmacology research to investigate NMDA-mediated neurotransmission.
- Selective competitive NMDA receptor antagonist
- Orally active with demonstrated in vivo anticonvulsant effects
- Shows antidepressant- and anxiolytic-like effects in rodent studies
- Chemical formula: C6H12NO5P; molecular weight: 209.14 g·mol-1
- Supplied in small milligram quantities suitable for research use
Hampton Research HR2-819/1.0 M Imidazole pH 7.0 - 100 ml
HR2-819/1.0 M Imidazole pH 7.0 - 100 ml. Please note items from this supplier are non-returnable.
Hampton Research HR2-930-D2/Grid Screen MPD #D2, 185 ml - 0.1 M Sodium acetate trihydrate pH 5.0, 65% (+/-)-2-Methyl-2,4-pentanediol
HR2-930-D2/Grid Screen MPD #D2, 185 ml - 0.1 M Sodium acetate trihydrate pH 5.0, 65% (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.
Hampton Research HR2-932-B6/Grid Screen Sodium Chloride #B6/Grid Screen Salt HT (G12), 185 ml - 0.1 M BICINE pH 9.0, 2.0 M Sodium chloride
HR2-932-B6/Grid Screen Sodium Chloride #B6/Grid Screen Salt HT (G12), 185 ml - 0.1 M BICINE pH 9.0, 2.0 M Sodium chloride. Please note items from this supplier are non-returnable.
Hampton Research HR2-906-17/StockOptions Bis-Tris #17 pH 7.1, 185 ml
HR2-906-17/StockOptions Bis-Tris #17 pH 7.1, 185 ml. Please note items from this supplier are non-returnable.
Hampton Research HR2-906-19/StockOptions Bis-Tris #19 pH 7.3, 185 ml
HR2-906-19/StockOptions Bis-Tris #19 pH 7.3, 185 ml. Please note items from this supplier are non-returnable.
Hampton Research HR2-907-22/SaltRx 1 #22 (B10), 185 ml - 1.2 M Sodium citrate tribasic dihydrate, 0.1 M Tris pH 8.5
HR2-907-22/SaltRx 1 #22 (B10), 185 ml - 1.2 M Sodium citrate tribasic dihydrate, 0.1 M Tris pH 8.5. Please note items from this supplier are non-returnable.