Protein Purification
MilliporeSigma™ Calbiochem™ Anaphase-Promoting Complex Inhibitor, TAME
The Anaphase-Promoting Complex Inhibitor, TAME, also referenced under CAS 1784-03-8, controls the biological activity of Anaphase-Promoting Complex. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ AMPK Activator
The AMPK Activator, also referenced under CAS 849727-81-7, modulates the biological activity of AMPK. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ InSolution™ AMPK Inhibitor, Compound C
InSolution™ AMPK Inhibitor, Compound C, CAS 866405-64-3, is a 10 mM (1 mg/250 μl) solution of AMPK Inhibitor, Compound C (Cat. No. 171260) in DMSO.
MilliporeSigma™ Calbiochem™ InSolution™ Smoothened Agonist, SAG
InSolution™ Smoothened Agonist, SAG, is a 10 mM (500 μg/86 μl) solution of Smoothened Agonist, SAG (Cat. No. 566660) in H2O.
MilliporeSigma™ Calbiochem™ Wnt Pathway Inhibitor XI, CCT036477
The Wnt Pathway Inhibitor XI, CCT036477, also referenced under CAS 305372-78-5, controls the biological activity of Wnt Pathway. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Piperlongumine
A cell-permeable, orally bioavailable natural product isolated from the plant species, Piper longum L, which selectively induces cell death in cancer cells that express both wild-type and mutant p53.
Cytiva Streptavidin Sepharose High Performance Resin
Affinity chromatography resin designed for fast and reliable, high resolution purification of biotinylated biomolecules.
MilliporeSigma™ Calbiochem™ Phenylmethylsulfonyl Fluoride
Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues.
MilliporeSigma™ Calbiochem™ o-Phenanthroline
A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells.
MilliporeSigma™ Calbiochem™ PERK Inhibitor I, GSK2606414
GSK2606414 is a cell-permeable, highly potent inhibitor of EIF2AK3/PERK (IC50 = 0.4 nM; [ATP] = 5 μM). Targets PERK in its inactive DFG conformation at the ATP-binding region.
MilliporeSigma™ Calbiochem™ Pepstatin A, Synthetic
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
MilliporeSigma™ Calbiochem™ PPACK, Dihydrochloride
PPACK, Dihydrochloride, CAS 142036-63-3, is an extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry.
Cytiva HiTrap Capto MMC Columns
HiTrap Capto MMC is prepacked with Capto MMC, a multimodal BioProcess ion exchange medium. The multimodal functionality gives a different selectivity compared with traditional ion exchangers and it binds proteins at high or low ionic strength.
Cytiva GSTrap™ HP Columns
Use to provide high-resolution, one-step purifications of glutathione S-Transferase (GST) tagged proteins. Cytiva Life Sciences™ GSTrap™ HP Columns are prepacked with Glutathione Sepharose™ High Performance medium.
Cytiva Ni Sepharose™ High Performance Media
Precharged with Ni2+ for optimal purification of histidine-tagged proteins. Cytiva Lifescience™ Ni Sepharose™ High Performance Media shows high binding capacity and compatibility.