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The PI 3-Kγ Inhibitor II, also referenced under CAS 648449-76-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 μl or 10 mg/924 μl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.
Used in affinity chromatography, protein chromatography and gel filtration chromatography. Sephadex™ G-25 is a gel filtration medium that has been used to study the acceleration of diabetic wound healing and the treatment of epithelial damage.
A cell-permeable compound that reversibly blocks cellular glycosylation and surface expression of Notch, APP, Klotho by blocking events prior to cargo assembly at the ER exit sites.
The PI 3-Kγ/CKII Inhibitor, also referenced under CAS 1138220-19-5, controls the biological activity of PI 3-Kγ/CKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
InSolution™ LY 294002, CAS 154447-36-6, is a 10mm solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4μM).
The Hedgehog Antagonist VIII, also referenced under CAS 330796-24-2, controls the biological activity of Hedgehog. This small molecule/inhibitor is primarily used for Cell Signaling applications.
A cell-permeable, restricted form of CCG-1423 with enhanced potency (IC50 = 4.2 μM vs 16.6 μM for PC-3 cell migration), but reduced off-target toxicity.