Protein. The extracellular domain of mouse Tim-4 aa 22-279 is fused to the N-terminus of the Fc region of human IgG1. Source CHO cells. Endotoxin content <0.05EU/µg protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in PBS. Purity >95% SDS-PAGE. Extracellular vesicles EVs are released by a variety of cells into the cellular microenvironment and have the natural ability of delivering different cargos and carry bioactive molecules such as non-coding RNA, miRNAs, genomic DNA, lipids, growth factors and signaling molecules. EVs can be divided into exosomes 30-100nm, microvesicles 100-1000nm and apoptotic bodies >1000nm. EVs play substantial roles not only in the regulation of normal physiological processes but also in disease pathogenesis and their cargo reflects the status of parental cells at the time of secretion. Various studies are currently being conducted to develop therapeutic and diagnostic methods targeting or utilizing EVs.