Protease Inhibitors and Phosphatase Inhibitors
Cayman Chemical ProstaglndIn D2 InhIbItr 10mg
A PGD2 receptor antagonist (DP; IC50 = 0.3 nM); inhibits PGD2-induced cAMP accumulation in LS 174T cells that endogenously express the DP receptor
Abcam RHC-80267, diacylglycerol lipase inhibitor, 50MG
MW 394.5 Da, Purity >98%. Selective diacylglycerol lipase inhibitor (IC₅₀ = 4 μM). Enhances acetylcholine induced smooth muscle relaxation in vitro.
The product is subject to the following: Abcam Restricted Use Statement
CPC Scientific H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (trifluoroacetate salt) 1MG
Inhibitor of gelatinases but not other MMP family members. When combined with tumor targeting, anti-invasive properties, it became a potential lead compound for the development of peptide-mimetic anticancer agents. ONE-LETTER SEQUENCE: CTTHWGFTLC (Cys1 and 10 bridge)MOLECULAR FORMULA: C52H71N13O14S2MOLECULAR WEIGHT:1166.33STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [244082-19-7], RESEARCH AREA: CancerREFERENCES: E.Koivunen et al, Nature Biotechnol., 17, 768 (1999)
Cayman Chemical PI4KIII InhIbItr 3 5mg
An inhibitor of PI4KIIIβ (IC50 = 19 nM); ~100-fold selective for PI4KIIIβ over PI4KIIα, PI4KIIβ, and PI4KIIIα, PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ, and PI3KC3, as well as 100-500-fold selective over PI3KC2α, PI3KC2β, and PI3KC2γ
Cayman Chemical PP1Src InhIbItr 25mg
A potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases: p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM)
Medchemexpress LLC HY-107702 5mg Medchemexpress, CGP 37849 CAS:127910-31-0 Purity:>98%
Medchemexpress, HY-107702 5mg CGP 37849 CAS:127910-31-0 CGP 37849 is a potent, competitive and orally active N-methyl-D-aspartate (NMDA) receptor antagonist. CGP 37849 is an anticonvulsant in rodents and has antidepressant and anxiolytic-like effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Cdk46 InhIbItr IV 1mg
A cell-permeable triaminopyrimidine that selectively and reversibly blocks Cdk4/cyclin D1 and Cdk6/cyclin D1 activity (IC50s = 1.5 and 5.6 μM, respectively); induces cell cycle arrest in the G1 phase and apoptosis in asynchronous cell lines; suppresses tumor growth in mice bearing human HCT116 colon carcinoma xenografts
Selleck Chemical LLC Spautin-1 10mg 1262888-28-7
Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating activity of USP10 and USP13 with IC50 of ?0.6-0.7 ?M. Spautin-1 enhances apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences CDC (10mg). CAS: 132465-11-3
Selective 12-lipoxygenase inhibitor. IC50=0.063 µM, 3.33 µM and 1.89 µM for 12-, 15- and 5-LO respectively in isolated enzyme preparations. Purity: ≥98%. Solubility: Soluble in ethanol (5mg/ml) or DMSO (5mg/ml). Long Term Storage: Ambient.
CPC Scientific DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH (trifluoroacetate salt) 0.5MG
ONE-LETTER SEQUENCE: DNP-PLALWARMOLECULAR FORMULA: C46H65N13O12MOLECULAR WEIGHT:992.1STORAGE CONDITIONS: -20 5CRESEARCH AREA: CancerREFERENCES: S. Netzel-Arnett, et al., Anal. Biochem. 195, 86 (1991)
TARGETMOL CHEMICALS INC SAQUINAVIR 50MG
Also available in 5 mg 10 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. purity: 100%
Abcam Wnt/b-Catenin Pathway Modulator Set, 1KIT
Wnt/b-Catenin Pathway Modulator Set (ab284178) is part of the multiplex kits range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Wortmannin 5mg 19545-26-7 KY 12420
Wortmannin (KY 12420) is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1 activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Abcam E-64d (Alo x istatin), cathepsin B and L inhibitor, 5MG
MW 342.4 Da, Purity >98%. Irreversible cell-permeable cathepsin B and L inhibitor. Inhibits calpain. Inhibits autophagy. Inhibits platelet proteolysis. Reduces brain amyloid-β levels. Shows neuroprotective effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Akt1/2 kinase inhibitor 985MG
Akt1/2 kinase inhibitor 985MG