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Cocktails, tablets, capsules, and individual purified formulations of protease inhibitors and phosphatase inhibitors designed to protect proteins from degradation during cell lysis and extraction.
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Competitive serine protease inhibitor which forms stable complexes with and blocks the active sites of enzymes. The binding is reversible, and most aprotinin-protease complexes dissociate at a pH>10 or <3.2. Target enzumes include trypsin, chymatrypsin, kalikrein and plasmin.
Activity: >4500 KIU/mg
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BRM/BRG1 ATP inhibitor-1 is an orally active, allosteric small-molecule inhibitor that selectively targets the ATPase activity of BRM (SMARCA2) and BRG1 (SMARCA4). It demonstrates sub-nanomolar potency and has shown anticancer activity in preclinical studies, making it useful for epigenetic and chromatin remodeling research.
Potent allosteric dual inhibitor of BRM and BRG1 ATPase activity.
Sub-nanomolar potency (IC50 < 0.005 μM) for both targets.
High purity suitable for biochemical and cell-based assays.
Available in solid and solution formats, including 10 mg solid and 10 mM in DMSO.
Recommended storage conditions preserve stability (powder: -20°C; in solvent: -80°C).
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Multi-kinase inhibitor 1 (CAS 778274-97-8) is a small molecule designed to concurrently inhibit multiple receptor tyrosine kinases including VEGFR PDGFR FGFR and c-Kit By targeting these signaling pathways the compound interferes with processes fundamental to tumor cell proliferation angiogenesis and metastasis Multi-kinase inhibitor 1 is utilized in biomedical research to explore the roles of these kinases in cancer biology model multi-targeted therapeutic strategies and assess the impact of broad-spectrum kinase inhibition on tumor growth and progression
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RNase Block is a 50-kDa protein that specifically inhibits common eukaryotic RNases including RNase A, RNase B and RNase C. It inactivates RNases by binding noncovalently to the RNase molecule.Only 25 to 40 U is required .
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E-64 research grade Inhibitor for papain and other cysteine (thiol) proteases. Effects on metastasis formation in mice (5). Size - 5MG Storage Conditions - -15 °C TO -25 °C Catalog Number - 21100.01 CAS 66701-25-5
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E-64 research grade Inhibitor for papain and other cysteine (thiol) proteases. Effects on metastasis formation in mice (5). Size - 25MG Storage Conditions - -15 °C TO -25 °C Catalog Number - 21100.02 CAS 66701-25-5
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PKC Isoenzyme Inhibitor PKC Y translocation peptide - 1mg , Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH Category/Application: Inhibitor This item is non returnable
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A B2-AR agonist selectively induces cAMP accumulation in CHO cells expressing the B2-AR over the B1- and B3-ARs (EC50s 0.4 398 and 794 nM for the human receptors respectively) inhibits contractions induced by electrical stimulation in isolated superfused guinea pig trachea strips inhibits histamine-induced bronchospasms in guinea pigs when administered via nebulization (EC50 30 UM)
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BODIPY FL PI(3)P (BODIPY FL Phosphatidylinositol 3-phosphate) is a water soluble analog of PI(3)P labeled with the green fluorophore, Bodipy-FL at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. This item is non returnable
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