Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ MICAL-2 Inhibitor II, CCG-203971
A cell-permeable, restricted form of CCG-1423 with enhanced potency (IC50 = 4.2 μM vs 16.6 μM for PC-3 cell migration), but reduced off-target toxicity.
![MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride](https://assets.fishersci.com/TFS-Assets/CCG/product-images/F584162~p.eps-250.jpg)
MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride
Chemically-modified forskolin with greater stability and water solubility than the parent compound.
MilliporeSigma™ Calbiochem™ Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose
2F-Peracetyl-Fucose is a cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic.
MilliporeSigma™ Calbiochem™ p53-Snail binding Inhibitor, GN25
The p53-Snail binding Inhibitor, GN25 controls the biological activity of p53-Snail. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Plasminogen Activator Inhibitor-1, Human, Recombinant
Primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Polo-like Kinase Inhibitor II, BTO-1
The Polo-like Kinase Inhibitor II, BTO-1, also referenced under CAS 40647-02-7, controls the biological activity of Polo-like Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor IV
A cell-permeable inhibitor of SKP2-dependent p27Kip1 ubiquitination. Selectively induces the accumulation SCFSKP2 substrates in multiple myeloma RPMI 8226 cells.
MilliporeSigma™ Calbiochem™ REV-ERBα Agonist, GSK4112
The REV-ERBα Agonist, GSK4112 controls the biological activity of REV-ERBα. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Calmodulin Kinase IINtide
A potent and specific inhibitor of CaMK II (IC50 = 50 nM for both the total and Ca2+-independent CaMK II activity).
MilliporeSigma™ Calbiochem™ Cdk1/2 Inhibitor III
The Cdk1/2 Inhibitor III, also referenced under CAS 443798-55-8, controls the biological activity of Cdk1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Daidzein
Inactive analog of Genistein.
MilliporeSigma™ Calbiochem™ CaMKII Inhibitor, CK59
The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Necrostatin-1
Necrostatin-1, CAS 4311-88-0, is a cell-permeable, potent, and selective blocker of necroptosis (EC50 = 494 nM in FADD-deficient Jurkat cells treated with TNF-α).
MilliporeSigma™ Calbiochem™ JAK3 Inhibitor I
The JAK3 Inhibitor I, also referenced under CAS 202475-60-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Rac1 Inhibitor
Rac1 Inhibitor, CAS 1177865-17-6, is a cell-permeable, reversible inhibitor of Rac1 GDP/GTP exchange. Interferes with the interaction between Rac1 and Rac-specific GEFs Trio and Tiam1 (IC50 ≈50 μM).