Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Phloretin
A cell-permeable inhibtor of protein kinase C (IC50 = 20-50 μM).
MilliporeSigma™ Calbiochem™ InSolution™ Etomoxir
A 50 mM (2 mg/118 μL) solution of Etomoxir in H2O.
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor XII, SPI
The STAT3 Inhibitor XII, SPI controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Cathepsin K Inhibitor I
The Cathepsin K Inhibitor I controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor III
A cell-permeable benzothiazolylchromenone compound that disrupts Skp2-Skp1 interaction via direct Skp2 affinity binding and selectively prevents Skp2-, but not Fbw7- or β-TrCP-, Skp1-Cullin-1-F-box (SFC) complex-mediated substrates ubiquitination, effectively preventing Skp2 substrates activation (Akt) and degradation (p21 & p27) with concomitant down-regulation of cellular Skp2 protein level (10 to 20μM in HEK293T & PC3 cultures)
MilliporeSigma™ Calbiochem™ Bradykinin
Induces the release of nitric oxide.
MilliporeSigma™ Calbiochem™ Ornithine Decarboxylase Inhibitor, POB
The Ornithine Decarboxylase Inhibitor, POB controls the biological activity of Ornithine Decarboxylase.
MilliporeSigma™ Calbiochem™ Ellipticine
A cell-permeable antitumor alkaloid that acts as an inhibitor of topoisomerase II and acts as an intercalative agent that stimulates topoisomerase II-mediated DNA breakage.
MilliporeSigma™ Calbiochem™ Lck Inhibitor
The Lck Inhibitor, also referenced under CAS 213743-31-8, controls the biological activity of Lck. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Fluoxetine, Hydrochloride
A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI).
MilliporeSigma™ Calbiochem™ Vinblastine Sulfate
Antitumor alkaloid drug.
MilliporeSigma™ Calbiochem™ Iron Chelator IV, 21H7
The Iron Chelator IV, 21H7 controls the biological activity of iron-regulated enzymes. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ AG 1478
Highly potent and specific inhibitor of the epidermal growth factor (EGF) receptor tyrosine kinase (IC50 = 3nM)
MilliporeSigma™ Calbiochem™ CGP 7930
A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB recep
MilliporeSigma™ Calbiochem™ MreB Perturbing Compound A22
A cell-permeable isothiourea compound that specifically, rapidly and reversibly perturbs MreB function without affecting eukaryotic actin polymerization.