Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Caspase Inhibitor II
The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ (±)-Ibuprofen
A nonsteroidal anti-inflammatory drug (NSAID) that acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC50 = 4.85 μM).
MilliporeSigma™ Calbiochem™ Apamin, Bee Venom
Polypeptide neurotoxin known to pass through the blood-brain barrier.
MilliporeSigma™ Calbiochem™ Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose
2F-Peracetyl-Fucose is a cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic.
MilliporeSigma™ Calbiochem™ PTP Inhibitor V, PHPS1
The PTP Inhibitor V, PHPS1, also referenced under CAS 314291-83-3, controls the biological activity of PTP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Latrunculin A, Latrunculia magnifica
Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM).
MilliporeSigma™ Calbiochem™ MMP-12 Inhibitor, MMP408
The MMP-12 Inhibitor, MMP408, also referenced under CAS 1258003-93-8, controls the biological activity of MMP-12. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Staurosporine, Streptomyces sp.
Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC50 = 7, 20, 1.3, 0.7, & 8.5 nM for PKA, CAMK, MLCK, PKC, & PKG, respectively).
MilliporeSigma™ Calbiochem™ LY 83583
A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ cFMS Receptor Inhibitor IV
The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Chelerythrine Chloride
Naturally-occurring alkaloid.
MilliporeSigma™ Calbiochem™ Cdk2 Inhibitor III
The Cdk2 Inhibitor III, also referenced under CAS 199986-75-9, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Chymostatin
Contains chymostatin A as a major form.
MilliporeSigma™ Calbiochem™ mTOR Inhibitor XI, Torin1
mTOR Inhibitor XI, Torin1, CAS 1222998-36-8, is a cell-permeable, highly potent, ATP-competitive inhibitor of mTOR and DNA-PK (IC50 = 4.32 and 6.34 nM, respectively).
MilliporeSigma™ Calbiochem™ SIRT1/2/3 pan Inhibitor
A thienopyrimidinylcarboxamide that acts as a highly potent, reversible pan sirtuin (SIRT) inhibitor (IC50 = 15, 10, and 33nM for SIRT1, 2, and 3, respective