Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor IV, SB-216763
A cell-permeable (aryl,indole) maleimide compound that acts as a potent, selective, ATP-competitive inhibitor of GSK-3 activity (Ki
MilliporeSigma™ Calbiochem™ 5,7-Dichlorokynurenic Acid, Sodium Salt
A very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79 nM
MilliporeSigma™ Calbiochem™ PKM2 Activator IV, TEPP-46
A cell-permeable, potent, allosteric activator of PKM2 (AC50 = 92 nM).
MilliporeSigma™ Calbiochem™ Oxymetazoline Hydrochloride
Oxymetazoline Hydrochloride is an α2-Adrenergic receptor agonist. Enhances EGF- and PDGF-induced DNA synthesis.
MilliporeSigma™ Calbiochem™ RHC-80267
Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells.
MilliporeSigma™ Calbiochem™ SIRT1 Inhibitor III
The SIRT1 Inhibitor III, also referenced under CAS 49843-98-3, controls the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Nedd4/Rsp5 Signaling Inducer, NAB2
A cell-permeable compound that protects against alpha-synuclein toxicity.
MilliporeSigma™ Calbiochem™ Zinc (II) Protoporphyrin IX
A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin.
MilliporeSigma™ Calbiochem™ Spermidine, Trihydrochloride
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.
MilliporeSigma™ Calbiochem™ InSolution™ IKK-2 Inhibitor, SC-514
The InSolution™ IKK-2 Inhibitor, SC-514 controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Paclitaxel, Semi-Synthetic
A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
MilliporeSigma™ Calbiochem™ Calcineurin Substrate
An excellent peptide substrate for calcineurin.
MilliporeSigma™ Calbiochem™ Calyculin A, Discodermia calyx
Calyculin A, CAS 101932-71-2, is a cell-permeable inhibitor of protein phosphatase 2A (IC50 = 0.5-1 nM) and protein phosphatase 1 (PP1; IC50 = 2 nM).
MilliporeSigma™ Calbiochem™ CA-074
CA-074, also referenced under CAS 134448-10-5, modulates the biological activity of cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ CaMKII Inhibitor, CK59
The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.