Protease Inhibitors and Phosphatase Inhibitors
Cayman Chemical MyelopRoxIdase InhIbItr Scr
A state-dependent sodium channel inhibitor selectively binds to inactivated Nav channels over resting Nav channels (Kis 0.6 and 15 UM respectively) inhibits INa in primary rat acutely dissociated hippocampal neurons at 1 UM inhibits early- and late-phase nociceptive responses in the formalin test in mice (ED50s 10.6 and 5.2 mg/kg respectively) reduces the number of MES-induced tonic seizures in mice and rats
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
502906714 AKT1/2 KINASE INHIBITOR 9825MG
Cayman Chemical AG-1478, 153436-53-4, 1 mg
Molecular Formula C16H14ClN3O2, Purity ≥98%, Formula Weight 315.8, Synonyms: N-(3-chlorophenyl)-6,7-dimethoxy-4-quinazolinamine, NSC 693255, Tyrphostin AG-1478; An inhibitor of EGFR kinase with an IC50 value of 3 nM.
Cayman Chemical (S)-MG132, 133407-82-6, 1 mg
A potent, reversible, and cell permeable proteasome inhibitor; inhibits cell growth in B16 and IPC227F cells with IC50 values of 42 and 77 nM, respectively; inhibits NF-κB activation, sensitizing a variety of carcinoma cell lines to apoptosis
Cayman Chemical (S)-MG132, 133407-82-6, 5 mg
A potent, reversible, and cell permeable proteasome inhibitor; inhibits cell growth in B16 and IPC227F cells with IC50 values of 42 and 77 nM, respectively; inhibits NF-κB activation, sensitizing a variety of carcinoma cell lines to apoptosis