Protease Inhibitors and Phosphatase Inhibitors
Cayman Chemical L-NMMA (acetate), 53308-83-1, 25 mg
Molecular Formula C7H16N4O2 • C2H4O2, Purity ≥99%, Formula Weight 248.3, Synonyms: L-NG-monomethyl Arginine acetate; A relatively non-selective inhibitor of all NOS isoforms with Ki values 0.18, 0.4, and 6 M for nNOs (rat), eNOS (human), and iNOS (mouse), respectively.
Cayman Chemical AG-1478, 153436-53-4, 1 mg
Molecular Formula C16H14ClN3O2, Purity ≥98%, Formula Weight 315.8, Synonyms: N-(3-chlorophenyl)-6,7-dimethoxy-4-quinazolinamine, NSC 693255, Tyrphostin AG-1478; An inhibitor of EGFR kinase with an IC50 value of 3 nM.
Cayman Chemical Garcinol, 78824-30-3, 10 mg
An inhibitor of the HATs p300 and pCAF (IC50 = 7 and 5 μM, respectively) that also inhibits the HAT Gcn5; promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells; induces apoptosis in several types of cancer cells and has anti-inflammatory actions
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3983074 A-CHYMOTRYSIN PROTEASE 25UG
Cayman Chemical (S)-MG132, 133407-82-6, 1 mg
A potent, reversible, and cell permeable proteasome inhibitor; inhibits cell growth in B16 and IPC227F cells with IC50 values of 42 and 77 nM, respectively; inhibits NF-κB activation, sensitizing a variety of carcinoma cell lines to apoptosis
Cayman Chemical MyelopRoxIdase InhIbItr Scr
A state-dependent sodium channel inhibitor selectively binds to inactivated Nav channels over resting Nav channels (Kis 0.6 and 15 UM respectively) inhibits INa in primary rat acutely dissociated hippocampal neurons at 1 UM inhibits early- and late-phase nociceptive responses in the formalin test in mice (ED50s 10.6 and 5.2 mg/kg respectively) reduces the number of MES-induced tonic seizures in mice and rats
Cayman Chemical Erlotinib, 183321-74-6, 250 mg
Molecular Formula C22H23N3O4, Purity ≥98%, Formula Weight 393.4, Synonyms: NSC 718781; A tyrosine kinase inhibitor which inhibits EGFR-associated kinase activity (IC50 = 2.5 M) and tumor growth in human HN5 tumor xenografts in mice with an ED50 value of 9 mg/kg; suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 M) and JAK2 mutant JAK2V617F positive hematopoietic progenitor cells (IC50 = 5 M).
Cayman Chemical DBZ 5MG
N-((1S)-2-(((7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz(b,d)azepin-7-yl)amino)-1-methyl-2-oxoethyl)-3,5-difluoro-benzeneacetamide | Purity: ≥98% | 209984-56-5 | 5mg
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC4010099 MUCINASE STCE PROTEASE
StemRD THIAZOVIVIN RCK INHIBITR 25MG
Chemicals, Cell Culture Media and Reagents, Thiazovivin, ROCK inhibitor, 25 mg
Cayman Chemical LY294002, 154447-36-6, 10 mg
Molecular Formula C19H17NO3, Purity ≥98%, Formula Weight 307.3; A selective PI3K inhibitor with an IC50 value of 1.4 M.