Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ TOFA
A cell-permeable furoic acid compound that acts as a potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme involved in the fatty acid biosynthesis.
MilliporeSigma™ Calbiochem™ Melatonin
A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.
MilliporeSigma™ Calbiochem™ Fbxo3 Inhibitor, BC-1215
A cell-permeable, bis-pyridinylbenzylethanamine that disrupts Fbxo3-Fbxl2 interaction and effectively prevents SCF-Fbxo3-catalyzed Fbxl2 ubiquitination, resulting in cellular Fbxl2 upregulation and thereby SCF-Fbxl2-catalyzed TRAFs (TNF Receptor-Associated Factors) ubiquitination
MilliporeSigma™ Calbiochem™ VEGFR Tyrosine Kinase Inhibitor VI, AAL-993
The VEGFR Tyrosine Kinse Inhibitor VI, ALL-993, also referenced under CAS 269390-77-4, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Proteasome Inhibitor Set I
The Proteasome Inhibitor Set I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ MCT1 Inhibitor, SR13800
A cell-permeable inhibitor of monocarboxylate transporter 1 (MCT1). Blocks the proliferation of Raji Burkitt lymphoma cells expressing MCT1 (EC50 = 5 nM).
MilliporeSigma™ Calbiochem™ p38 MAP Kinase Inhibitor VII, SD-169
The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase.
MilliporeSigma™ Calbiochem™ Sphingosine Kinase Inhibitor
The Sphingosine Kinase Inhibitor, also referenced under CAS 1177741-83-1, controls the biological activity of Sphingosine Kinase. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Bupropion Hydrochloride
Bupropion is a non-selective inhibitor of dopamine and noradrenalin transporters. Also an antagonist for neuronal nicotinic acetylcholine receptors (nAChrs).
MilliporeSigma™ Calbiochem™ Menin-MLL Interaction Inhibitor, MI-2-2
A cell-permeable thienopyrimidine compound
MilliporeSigma™ Calbiochem™ 17-AAG
A less toxic, potent, synthetic derivative of the ansamycin benzoquinone antibiotic Geldanamycin, Streptomyces hygroscopicus.
MilliporeSigma™ Calbiochem™ Vigabatrin
A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties
Aprotinin, Analytical Grade, MP Biomedicals™
Forms stable complexes with enzymes. Aprotinin, Analytical Grade, MP Biomedicals is a competitive serine proteinase inhibitor that works by blocking the active sites of enzymes. This binding is reversible with most aprotinin-protease complexes, dissociati
MilliporeSigma™ Calbiochem™ Brk Inhibitor, Cpd 4f
A cell permeable, highly potent, and very selective inhibitor of breast tumor kinase (Brk; IC50 = 3.15 nM). Displays anti-proliferative activity against multiple breast cancer cell lines.
MilliporeSigma™ Calbiochem™ L-N5-(1-Iminoethyl)ornithine, Dihydrochloride
A cell-permeable, more potent inhibitor of endothelial nitric oxide synthase compared to other arginine analogs such as L-NAME and L-NMMA.