Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Photochromic TrpA1 Channel Activator, Optovin
A rhodanine-derived, reversible, photoactivated, TrpA1-selective channel activator.
MilliporeSigma™ Calbiochem™ Stauprimide
A cell-permeable ESCs (Embryonic Stem Cells) EMT (Epithelial-Mesenchymal Transition) inducer that is reported to prime/sensitize human and murine ESC cultures for much more enhanced/efficient differentiation into progenitor cells of multiple lineages.
MilliporeSigma™ Calbiochem™ ERO1 Inhibitor II, EN460
A cell-permeable thiol reactive enone (EN) compound that selectively interacts with the active-site cysteine of reduced, active form of ERO1α and inhibits its activity (IC50
MilliporeSigma™ Calbiochem™ InSolution™ SB 203580
InSolution SB 203580, CAS 152121-47-6, is a 1mg/mL solution of SB 203580 in DMSO. A cell-permeable, selective, reversible inhibitor of p38 MAP kinase (IC50 = 34nM in vitro, 600nM in cells).
MilliporeSigma™ Calbiochem™ S-Methyl-L-thiocitrulline, Dihydrochloride
A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300nM) compared to the endothelial enzyme (IC50 = 5.4μM).
MilliporeSigma™ Calbiochem™ SRPK Inhibitor, SRPIN340
A cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50
MilliporeSigma™ Calbiochem™ InSolution™ Batimastat
A Marimastat type of peptidyl hydroxamate-based inhibitor that potently inhibits a broad-spectrum of metalloproteinases
MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor XII
The γ-Secretase Inhibitor XII controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Flumazenil
A competitive blocker of benzodiazepine activation of inhibitory GABAergic synpases (ID50 = 200μg/kg/i
MilliporeSigma™ Calbiochem™ IRE1 Inhibitor III, 4μ8C
IRE1 Inhibitor III, , CAS 14003-96-4, is a cell-permeable. Covalent inhibitor of IRE1 RNase activity (IC50 = 550 and 45 nM, respectively, with 0 & 16 min preincubation in RNA cleavage assays).
MilliporeSigma™ Calbiochem™ SB-269970 Hydrochloride
A selective 5-HT7 receptor antagon
MilliporeSigma™ Calbiochem™ InSolution™ SRT1720, HCl
A 25 mM (10 mg/650 μl) sterile-filtered solution of SRT1720, HCl in DMSO.
MilliporeSigma™ Calbiochem™ D-Amino Acid Oxidase Inhibitor III, AS057278
A cell-permeable pyrazolocarboxylic acid that acts as a selective D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) inhibitor (IC50 = 910nM against human DAO; [D-ser] = 10 mM) and effectively protects DAO overexpressing cultures from oxidative stress-induced cell death upon D-Ser (50 mM) exposure (ED50
MilliporeSigma™ Calbiochem™ InSolution™ Akt Inhibitor IV
The InSolution™ Akt Inhibitor IV controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ AhR Antagonist II, SR1
The AhR Antagonist II, SR1 controls the biological activity of AhR. This small molecule/inhibitor is primarily used for Biochemicals applications.