Protein Purification Reagents and Kits
AdipoGen VEGF-C human rec His
Protein. Human VEGF-C 115aa is fused at the C-terminus to a His-tag. Source Sf9 cells. Lyophilized. Purity >90% SDS-PAGE. VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 KDR/FLK1 and VEGFR-3 FLT4 receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
AdipoGen NADK M tuberculosis His
Protein. NAD kinase Mycobacterium tuberculosis is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 10mM TRIS at pH 8.0, containing 1mM MgCl2, 0.5mM EDTA, 1mM DTT and 1mM PMSF. Purity >98% SDS-PAGE. NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity ATP NAD = ADP NADP
Bioss Powassan virus
Powassan virus Primary Antibody Unconjugated Host Species Mouse Target Species Clonality Monoclonal Applications ELISA Concentration 100 g/ml Size 100 ug Storage Buffer PBS (pH 7 2) with 0 1% azide
AdipoGen IL-37 aa 46-218hrecHis
Protein. Human IL-37 aa Val46-Asp218 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >95% SDS-PAGE. IL-37 IL-1F7 IL-1H4 is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells PBMCs and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor IL-18R and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide LPS-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
AdipoGen DNER ED msFc h rec
Protein. Signal peptide and extracellular domain of mouse DNER aa 1-640 are fused at the C-terminus to the Fc portion of human IgG. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in PBS. Purity >85% SDS-PAGE. DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
AdipoGen IL-37 aa 46-218hrecHis
Protein. Human IL-37 aa Val46-Asp218 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >95% SDS-PAGE. IL-37 IL-1F7 IL-1H4 is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells PBMCs and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor IL-18R and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide LPS-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
AdipoGen HpARI rec His
Protein. Heligmosomoides polygyrus protein HpARI aa 17-251 is fused at the C-terminus to a His-tag. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Purity >90% SDS-PAGE. HpARI is a protein secreted by the mouse parasite Heligmosomoides polygyrus. The mature protein HpARI, containing three predicted Complement Control Protein CCP-like modules also known as Short Consensus Repeats SCRs or sushi-domains, suppresses type 2 allergic immune responses through interference in the interleukin-33 IL-33 pathway. During cell damage, HpARI gains access to the nucleus of necrotic cells, where it binds directly to IL-33 and nuclear DNA, preventing secretion and binding of IL-33 to its receptor. HpARI is a new type of reagent to prevent IL-33-mediated pathology.
Research Products International Corp ChIP DNA Clean and Concentrator w/Zymo-Spin IC Columns , Capped, 50 Preps
The Chromatin Immunoprecipitation (ChIP) DNA Clean & Concentrator provides a hassle-free method for the rapid purification and concentration of high-quality DNA from any step in a standard ChIP protocol. This includes samples that have undergone reverse cross-linking, Proteinase K or RNase A digestion, mechanical or nuclease-mediated DNA shearing, and samples eluted from chromatin-antibody-bead complexes. The specially formulated ChIP DNA Binding Buffer promotes DNA adsorption to the column in the presence of detergents, antibodies, and proteinases that are often used for ChIP.
Two minute DNA clean-up from any step in a standard ChIP protocol.
DNA is ideal for PCR, arrays, DNA quantification, Southern blot analysis, sequencing, and other molecular applications.
