Protein Purification Reagents and Kits
BIOHIPPO Anti-Human BRAF/B-Raf (V600E) Antibody (SAA2181), 100 µg
BRAF/B-Raf (SAA2181) Recombinant Antibody (clone V600E) is a recombinant Rabbit IgG, kappa antibody specific for BRAF/B-Raf (SAA2181). It reacts with Human. Suitable for ELISA. Recombinant production ensures high specificity and lot-to-lot reproducibility. Supplied as 100 ug.
BIOHIPPO Anti-Human BRAF/B-Raf Antibody (SAA1756), 100 µg
BRAF/B-Raf Recombinant Antibody (clone SAA1756) is a recombinant Mouse IgG2a, kappa antibody specific for BRAF/B-Raf. It reacts with Human. Suitable for ELISA. Recombinant production ensures high specificity and lot-to-lot reproducibility. Supplied as 100 ug.
Cayman Chemical GlutathIon ethyl ester 50mg
A cell-permeable derivative of GSH; increases mitochondrial GSH levels in C38 and IB3-1 epithelial lung cystic fibrosis cells at 10 mM; decreases reactive oxygen species (ROS) levels and TNF-α-induced IL-8 secretion in IB3-1 cells at 10 mM; increases mitochondrial complex I function and reduces depolarization of the mitochondrial membrane potential in IB3-1 cells at 10 mM and 1mM, respectively; decreases lipid oxidation and ferroptosis in cystine-deficient PANC-1, AsPC-1, BxPC-3, and S2-013 pancreatic cancer cells; increases the viability of irradiated human lymphoid cells at 5 mM
Proteintech Group Inc MBP-Trap Agarose beads
The ChromoTek MBP-Trap Agarose are affinity beads for IP of MBP-fusion proteins. They comprise MBP Nanobodies/ VHHs coupled to agarose beads.
Active Motif miRNA Target IP Kit
Active Motif's miRNA Target IP Kit was designed to identify the physical interactions of a miRNA with endogenous mRNA transcripts. It utilizes protein G-coupled magnetic beads and a pan-Ago antibody to efficiently immunoprecipitate miRNA/mRNA complexes that have associated with Ago1, Ago2 or Ago3 proteins as part of a RISC complex. Following their immunoprecipitation, the mRNA targets are purified and then amplified by qRT-PCR using gene-specific primers. This makes it possible to validate the specific mRNA transcripts that are binding targets of that miRNA. It is also possible to profile the immunoprecipitated mRNA molecules using conventional expression microarrays or RNA-Seq.
American Research Products Inc Rat p53 tumor protein p53 TP5
Rat p53/tumor protein p53/TP53 ELISA Kit from CUSABIO Detection Range 12 5 pg/mL-800 pg/mL Sensitivity 3 12 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Abcam BVT 948, Protein tyrosine phosphatase (PTP) inhibitor, 50MG
MW 241.24 Da, Purity >99%. Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor (IC₅₀ values are 0.9 (PTP1B), 1.7 (TCPTP), 0.09 (SHP-2), 1.5 (LAR) and 0.7 (YopH) μM). Active in vivo and cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Zymo Research Corporation Methylated-DNA IP Kit, 10 Rxns.
The Methylated-DNA IP Kit enriches 5-methylcytosine (5-mC) containing DNA from any pool of fragmented genomic DNA for use in genome-wide methylation analysis.The kit includes a highly specific anti-5-methylcytosine monoclonal antibody for the “capture” and separation of methylated DNA from non-methylated DNA in only a fewhours. Typically, over a hundred-fold enrichment of methylated DNA vs. non-methylated DNA can be achieved with the use of this kit. Recovered DNA is suitable for many downstream applications to analyze genome-wide DNA methylation including: PCR, qPCR, whole-genome amplification, MeDIP-Seq, etc.
Cayman Chemical MK2 InhIbItr III 1mg
A potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM); less potently blocks MK3 and MK5 (IC50s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets; prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC50 = 4.4 µM)
Abcam Immunoprecipitation kit, 25 Tests
Abcam's Immunoprecipitation Kit (ab206996) can be used to perform immunoprecipitation (IP) and Co-IP for functional studies of immunoprecipitated proteins/complexes and SDS-PAGE or western blot analysis of immunoprecipitated proteins and complexes.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology MAPKAPK-2/MK2 Rabbit pAb
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
Proteintech Group Inc DYKDDDDK Fab-Trap™ Agarose
The ChromoTek DYKDDDDK Fab-Trap™ Agarose consists of an anti-DYKDDDDK-tag Fab-fragment, which is covalently bound to agarose beads. DYKDDDDK Fab-Trap™ Agarose is used to immunoprecipitate 1x and 3xDYKDDDDK-tagged fusion proteins from cell extracts of various organisms like mammals, plants, bacteria, yeast, insects etc.
Active Motif ChIP-IT High Sensitivity
The ChIP-IT High Sensitivity (HS) Kit is designed to give superior performance when performing ChIP using antibodies against low abundance transcription factors, antibodies with sub-optimal binding affinities or when starting with a limited number of cells. Higher signal and lower non-specific DNA pulldown is achieved through the incorporation of specialized protein G agarose beads and optimized fixation, binding and wash buffers. In addition, washes are performed via gravity filtration, which is faster, easier and more consistent than magnetic bead capture. The high-quality ChIP DNA obtained from the ChIP-IT High Sensitivity Kit is also ideal for ChIP-Seq; ChIP-IT HS has been validated for use in this application, even when using antibodies that target low abundance transcription factors.
Abcam Pifithrin-alpha-HBr, p53 Inhibitor, 10MG
MW 367.3 Da, Purity >95%. p53 Inhibitor. Specifically blocks tumor supressor p53 transcriptional activity and can supress heat shock and glucocorticoid signalling pathways. Additionally offers protection to cells from p53 mediated apoptosis. Active in vivo; protects mice from chemotherapy side effects associated with p53 induction. Also aryl hydrocarbon receptor (AHR) agonist.
The product is subject to the following: Abcam Restricted Use Statement