HumaDerm is the only affordable lyophilized native human skin collagen for hydrogel, organoids, tissue modeling, bioink, and other regenerative medicine applications. The optimal concentration may vary depending on cell type and application and must be optimized for best results. It is soluble in dilute acid at pH ~2.0. It is isolated from human skin sourced strictly from American Association of Tissue Banks (AATB) accredited and FDA registered tissue banks and organ procurement organizations (OPOs). HumaDerm is manufactured under ISO 13485 certified and GMP-compliant quality systems. HumaDerm is obtained from human tissue that has been tested negative for a minimum of HIV-1 and -2, hepatitis B, and hepatitis C as well as other infectious agents. HumaDerm is for research use only and is not intended for human use, diagnosis, screening, household, food, or other uses. Lyophilized HumaDerm should be stored at -20 °C upon receipt.