Immunosuppressant Drug Testing Controls and Calibrators
Immunosuppressant Drug Testing Controls and Calibrators
- 1
- 2
Test
Obtain results you can count on for immunosuppressant drug monitoring with the Thermo Scientific™ QMS™ Everolimus Immunoassay.
Content And Storage | 2°C to 8°C |
---|---|
Sample Type | Whole Blood |
Detectable Analytes | Everolimus |
Accurately measure therapeutic drug levels in serum and plasma with Thermo Scientific™ QMS™ TDM Calibrators, offered in Levels A to F.
Content And Storage | 2°C to 8°C |
---|---|
Sample Type | Plasma,Serum |
Save time while maintaining accuracy with economical Thermo Scientific™ CEDIA™ Therapeutic Drug Monitoring (TDM) Calibrators, optimized for use with CEDIA TDM Assays.
Type | Calibrator |
---|---|
Content And Storage | 2°C to 8°C |
Sample Type | Plasma,Serum |
Quantity | Low: 2 x 7.5 mL; High: 2 x 5.0 mL |
Ensure accurate results when testing with the newest TDM reagents with Thermo Scientific™ QMS™ TDM Controls, offered in three levels.
Type | Control |
---|---|
Content And Storage | 2°C to 8°C |
Achieve excellent low-end precision and sensitivity with the Thermo Scientific™ QMS™ Tacrolimus Immunoassay.
Sample Type | Whole Blood |
---|---|
Detectable Analytes | Tacrolimus |
Complete your ISD panel with the Thermo Scientific™ CEDIA™ Mycophenolic Acid Immunoassay.
Content And Storage | 2°C to 8°C |
---|---|
Sample Type | Plasma |
Detectable Analytes | Mycophenolic Acid |
K-ASSAY Prealbumin Calibrator. 6 x 1 mL (liquid). For 6 point calibration. The K-ASSAY Prealbumin Calibrator is intended to be used for the calibration of the K-ASSAY Prealbumin immunoturbidimetric assay (Cat. No. KAI-053) for quantifying prealbumin in serum specimens. FOR IN VITRO DIAGNOSTIC USE.
Chemical. CAS 39831-55-5. Formula C22H43N5O13 . 2H2SO4. MW 781.76. Amikacin is a broad-spectrum aminoglycoside antibiotic and a semisynthetic analog of kanamycin. It irreversibly binds to 16S rRNA and the RNA-binding S12 protein of the 30S subunit and 50S subunit of prokaryotic ribosome and inhibits protein synthesis. It works in a concentration-dependent manner, and has better action in an alkaline environment. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains, due to its resistance to inactivating enzymes. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria. Amikacin can be used to treat non-tubercular mycobacterial infections and tuberculosis when first-line drugs fail to control the infection.
Technothrombin TGA (Thrombin Generation Assay) Control Low. Human plasma with decreased thrombin generation, lyophilized.
NC1897911 LDL-C CALIBRATOR
NC2000639 ANTIFUNGALS LEVEL 2 5/PK
For calibration of the various LDL Cholesterol Assays.
Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities.
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that shows improved pharmacokinetics and pharmacodynamics. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Since mTORC2 is believed to play an important role in glucose metabolism and the immune system, selective inhibition of mTORC1 achieves many of the benefits of rapamycin without the associated glucose intolerance and immunosuppression Anticancer agent.
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that shows improved pharmacokinetics and pharmacodynamics. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Since mTORC2 is believed to play an important role in glucose metabolism and the immune system, selective inhibition of mTORC1 achieves many of the benefits of rapamycin without the associated glucose intolerance and immunosuppression Anticancer agent.