Immunosuppressant Drug Testing Controls and Calibrators
Immunosuppressant Drug Testing Controls and Calibrators
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Test
Accurately measure therapeutic drug levels in serum and plasma with Thermo Scientific™ QMS™ TDM Calibrators, offered in Levels A to F.
Content And Storage | 2°C to 8°C |
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Sample Type | Plasma,Serum |
Save time while maintaining accuracy with economical Thermo Scientific™ CEDIA™ Therapeutic Drug Monitoring (TDM) Calibrators, optimized for use with CEDIA TDM Assays.
Type | Calibrator |
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Content And Storage | 2°C to 8°C |
Sample Type | Plasma,Serum |
Quantity | Low: 2 x 7.5 mL; High: 2 x 5.0 mL |
Obtain results you can count on for immunosuppressant drug monitoring with the Thermo Scientific™ QMS™ Everolimus Immunoassay.
Content And Storage | 2°C to 8°C |
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Sample Type | Whole Blood |
Detectable Analytes | Everolimus |
Achieve excellent low-end precision and sensitivity with the Thermo Scientific™ QMS™ Tacrolimus Immunoassay.
Sample Type | Whole Blood |
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Detectable Analytes | Tacrolimus |
Complete your ISD panel with the Thermo Scientific™ CEDIA™ Mycophenolic Acid Immunoassay.
Content And Storage | 2°C to 8°C |
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Sample Type | Plasma |
Detectable Analytes | Mycophenolic Acid |
Ensure accurate results when testing with the newest TDM reagents with Thermo Scientific™ QMS™ TDM Controls, offered in three levels.
Type | Control |
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Content And Storage | 2°C to 8°C |
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that shows improved pharmacokinetics and pharmacodynamics. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Since mTORC2 is believed to play an important role in glucose metabolism and the immune system, selective inhibition of mTORC1 achieves many of the benefits of rapamycin without the associated glucose intolerance and immunosuppression Anticancer agent.
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that shows improved pharmacokinetics and pharmacodynamics. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Since mTORC2 is believed to play an important role in glucose metabolism and the immune system, selective inhibition of mTORC1 achieves many of the benefits of rapamycin without the associated glucose intolerance and immunosuppression Anticancer agent.
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo.
NC2000638 ANTIFUNGALS LEVEL 1 5/PK
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo.
Medchem Express / Mycophenolic acid glucuronide / 1mg / 781212823 / HY-137301 / / 31528-44-6 / MFCD09878308 / 496.465 / C23H28O12
NC2953878 EVEROLIMUS 500MG
Human plasma with increased thrombin generation, lyophilized.
NC2236523 CTL2 CONNECTING CABLE 2M