Immunosuppressant Drug Testing Controls and Calibrators
Immunosuppressant Drug Testing Controls and Calibrators
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Test
Complete your ISD panel with the Thermo Scientific™ CEDIA™ Mycophenolic Acid Immunoassay.
Content And Storage | 2°C to 8°C |
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Sample Type | Plasma |
Detectable Analytes | Mycophenolic Acid |
Achieve excellent low-end precision and sensitivity with the Thermo Scientific™ QMS™ Tacrolimus Immunoassay.
Sample Type | Whole Blood |
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Detectable Analytes | Tacrolimus |
Ensure accurate results when testing with the newest TDM reagents with Thermo Scientific™ QMS™ TDM Controls, offered in three levels.
Type | Control |
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Content And Storage | 2°C to 8°C |
Save time while maintaining accuracy with economical Thermo Scientific™ CEDIA™ Therapeutic Drug Monitoring (TDM) Calibrators, optimized for use with CEDIA TDM Assays.
Type | Calibrator |
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Content And Storage | 2°C to 8°C |
Sample Type | Plasma,Serum |
Quantity | Low: 2 x 7.5 mL; High: 2 x 5.0 mL |
Accurately measure therapeutic drug levels in serum and plasma with Thermo Scientific™ QMS™ TDM Calibrators, offered in Levels A to F.
Content And Storage | 2°C to 8°C |
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Sample Type | Plasma,Serum |
Obtain results you can count on for immunosuppressant drug monitoring with the Thermo Scientific™ QMS™ Everolimus Immunoassay.
Content And Storage | 2°C to 8°C |
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Sample Type | Whole Blood |
Detectable Analytes | Everolimus |
Chemical. CAS 39831-55-5. Formula C22H43N5O13 . 2H2SO4. MW 781.76. Amikacin is a broad-spectrum aminoglycoside antibiotic and a semisynthetic analog of kanamycin. It irreversibly binds to 16S rRNA and the RNA-binding S12 protein of the 30S subunit and 50S subunit of prokaryotic ribosome and inhibits protein synthesis. It works in a concentration-dependent manner, and has better action in an alkaline environment. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains, due to its resistance to inactivating enzymes. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria. Amikacin can be used to treat non-tubercular mycobacterial infections and tuberculosis when first-line drugs fail to control the infection.
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo.
Medchem Express / Mycophenolic acid glucuronide / 1mg / 781212823 / HY-137301 / / 31528-44-6 / MFCD09878308 / 496.465 / C23H28O12
Human plasma with increased thrombin generation, lyophilized.
NC2236523 CTL2 CONNECTING CABLE 2M
NC2953878 EVEROLIMUS 500MG
2'-O-Methyl Uridine CED phosphoramidite, 20g
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo.
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that shows improved pharmacokinetics and pharmacodynamics. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Since mTORC2 is believed to play an important role in glucose metabolism and the immune system, selective inhibition of mTORC1 achieves many of the benefits of rapamycin without the associated glucose intolerance and immunosuppression Anticancer agent.