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A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DLin-M-C4-DMA, also known as Compound MC4, is a cationic lipid. It is primarily used for the effective delivery of nucleic acids in various research applications. This product is provided as a colorless to light yellow liquid.
Used for delivery of nucleic acids
Functions as a cationic lipid
Targets liposomes
Involves the metabolic enzyme/protease pathway
Appears as a colorless to light yellow liquid
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
1 2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a phospholipid used in the synthesis of liposomes and lipid nanoparticle (LNP) systems for research related to mRNA vaccines or drug delivery systems
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DSPE-PEG (2000)-COOH is a pegylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. This compound can form micelles, making it suitable for targeted drug delivery applications. It is intended for research use only.
Forms micelles for targeted drug delivery.
High purity: 99.95%.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DSPE-PEG2000-GE11 is a nanocarrier component composed of DSPE and the EGFR-targeting peptide (GE11). It specifically binds to EGFR, mediating receptor-mediated endocytosis of micellar drug carriers for drug delivery.
Specifically binds to EGFR.
Mediates receptor-mediated endocytosis of micellar drug carriers.
Enhances EGFR-dependent cellular uptake of doxorubicin (1.4-fold higher in SMMC-7721 cells).
Inhibits HUVEC proliferation, induces G2-M phase arrest, reduces cell migration, and alters HUVEC morphology when modified.
Enhances tumor accumulation of DiR-loaded micelles in EGFR-positive hepatocellular carcinoma xenografts.
Confers EGFR-targeted accumulation to liposomal formulations in liver cancer xenografts.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DPPE-PEG2000 ammonium is a PEG-modified phosphatidylethanolamine used in research to impart steric stabilization to liposomes and other lipid-based delivery systems. It reduces nonspecific protein adsorption and can prolong circulation time, and is commonly used in liposome preparation and in the formulation of PEG-MLPs and magnetoliposomes.
Reduces nonspecific protein adsorption on particle surfaces
Prolongs circulation time of lipid-based formulations
Suitable for liposome and lipid nanoparticle preparation
Available in small research quantities for formulation work
High purity (reported ~99.8%) and average molecular weight ~2700 Da
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More