Substrates
Sino Biological SwiftFluo TR-FRET CDKs Kinase Kit-Rb(S780) substrate 1000 Tests
SwiftFluo TR-FRET CDKs kinase kit is designed for measuring the cyclin-dependent kinases (CDKs) activity.
Medchemexpress LLC D-luciferin (sodium) | 103404-75-7 | 99.9% | 302.30 | C11H7N2NaO3S2 | 500MG
D-Luciferin sodium is the sodium salt of D-luciferin, the natural substrate for firefly luciferase used to generate bioluminescent signals in reporter assays and imaging. Supplied as a light yellow solid with high purity, it is suitable for in vitro and in vivo bioluminescence applications.
- Natural substrate for firefly luciferase.
- Produces bioluminescent signal for reporter assays and imaging.
- High purity (99.9%).
- Molecular weight 302.30.
- Formula C11H7N2NaO3S2.
- Available in multiple pack sizes, including 500 MG.
- Solid, light yellow to yellow appearance.
- Store sealed, away from moisture and light; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Ac-DEVD-AMC | 169332-61-0 | MFCD00671411 | 99.2% | 675.64 | 10 MG
Ac-DEVD-AMC is a fluorescent substrate for caspase-3/caspase-7. When treated with cell lysate, it releases amino-4-methylcoumarin (AMC) for fluorescence detection.
- Fluorescent substrate for caspase-3/caspase-7
- Releases amino-4-methylcoumarin (AMC) for fluorescence detection
- Excitation wavelength of 380 nm
- Emission wavelength of 460 nm
Medchemexpress LLC Bz-Phe-Val-Arg-AMC | 88899-22-3 | 99.8% | 681.78 g·mol⁻¹ | C37H43N7O6 | 10 MG
Bz-FVR-AMC is a fluorogenic peptide substrate used to monitor procathepsin and related protease activity. The substrate releases 7-amino-4-methylcoumarin (AMC) upon enzymatic cleavage and has an observed kcat/Km of 1,070 mM⁻¹·s⁻¹; at high concentrations it can inhibit the reaction. Typical handling: supplied as a solid and stored frozen to maintain stability.
- Releases the fluorescent AMC reporter upon enzymatic cleavage.
- Used to measure procathepsin and related protease activity in biochemical assays.
- Reported kcat/Km of 1,070 mM⁻¹·s⁻¹.
- High concentrations may inhibit protease activity.
- Supplied as a solid and stored at -20 °C to maintain stability.
- Reported purity about 99.8% and molecular weight 681.78 g·mol⁻¹.
Cayman Chemical cGAS TR-FRET DetectIon MIx 1ea
cGAS TR-FRET Detection Mix has been tested and formulated to work exclusively with Cayman’s cGAS TR-FRET Inhibitor Screening Assay Kit (Item No. 702120).
Bioworld IPTG (Isopropyl-B-D-ThioGalactopyranoside) Solution, 100mM, 10 mL
Isopropyl-β-D-Thiogalactopyranoside, an inducer of β-galactosidase is used to promote the expression of proteins in cells controlled by the lac operator system. Supplied as 1ml or 10x1ml of 100mM ready-to-use solution to be used with X-gal for blue white colony screening. Techncial Information:Biotechnology Grade.Ready-to-use solution Sterile filtered (0.22μM)Dioxane freeApplication: Petriplates: Use 40 μl per Petriplates (9 cm diameter). LB agar: Use 1μl/mL of liquid LB agar medium just before pouring (~50°C).Liquid culture: Use 1μl/mL of liquid culture medium.Sold as 1mL or 10 x 1mL.
Medchemexpress LLC Boc-Leu-Lys-Arg-AMC | 109358-47-6 | 96.9% | 672.82 | 1 MG
Boc-Leu-Lys-Arg-AMC is a fluorogenic substrate for the Kex2 endoprotease. It is for research use only and not sold to patients.
- Fluorogenic substrate
- Used for Kex2 endoprotease
- For research use only
- Available in various sizes
- Fluorescent dye
Medchemexpress LLC Boc-Gly-Lys-Arg-AMC | 109358-48-7 | 616.71 | 5 MG
Boc-Gly-Lys-Arg-AMC is a polypeptide identified through peptide screening. This research tool primarily uses immunoassay to pool active peptides. It can be utilized for protein interaction, functional analysis, and epitope screening, especially in agent research and development. This product is for research use only.
- Identified through peptide screening
- Primarily uses immunoassay to pool active peptides
- Utilized for protein interaction
- Suitable for functional analysis
- Can be used for epitope screening
- Aids in agent research and development
- For research use only
Medchemexpress LLC Boc-Gly-Lys-Arg-AMC | 109358-48-7 | 616.71 | 10 MG
Boc-Gly-Lys-Arg-AMC is a polypeptide used in peptide screening, a research tool that identifies active peptides primarily through immunoassay. This product is suitable for protein interaction studies, functional analysis, and epitope screening, particularly in agent research and development. It is intended for research use only.
- Polypeptide for peptide screening
- Used in protein interaction studies
- Suitable for functional analysis
- Ideal for epitope screening
- Research use only
- Chemical formula: C29H44N8O7
- Sequence: {Boc-Gly}-Lys-{Arg-AMC}
- Molecular weight: 616.71
Sino Biological Peptide Substrates: CDKtide
The CDKtide peptide sequence (CKKKYSPTSPSYSPTSPSY-SPTSPS) is derived from the C-terminus of the largest subunit of human RNA polymerase II which has 52 approximate tandem repeats of 7 amino acids Y-[ST]-P-[STQ]-[ST]-P-[SRTEVKGN]. This peptide is suitable as a substrate for CDK7, CDK8, CDK9 and CDK11.
![Research Products International Corp Magenta-Gal [5-Bromo-6-chloro-3-indolyl-B-D-galactopyranoside], 100 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-B73000-0.1.JPG-250.jpg)
Research Products International Corp Magenta-Gal [5-Bromo-6-chloro-3-indolyl-B-D-galactopyranoside], 100 Milligrams
Chromogenic substrate of β-Galactosidase. Produce magenta color.
Medchemexpress LLC ATR kinase substrate peptide | 1232497-16-3 | 99.3% | 1814.05 | 1 MG
ATR kinase substrate peptide (ASELPASQPQPFSAKKK) is a peptide substrate for ATR protein kinase. It can be utilized to detect ATR kinase activity.
- Functions as a peptide substrate for ATR protein kinase
- Utilized to detect ATR kinase activity
- Has a Ki value of 6 nM against ATR
- Features the sequence shortening ASELPASQPQPFSAKKK
Medchemexpress LLC Benzyloxycarbonyl-L-leucyl-L-leucyl-L-glutamic acid 7-amido-4-methylcoumarin | 348086-66-8 | MFCD01074989 | 99.5% | 664.75 g·mol⁻¹ | C35H44N4O9 | 50MG
Z-Leu-Leu-Glu-AMC is a fluorogenic peptide substrate for measuring postacidic-like (peptidylglutamyl-peptide hydrolyzing, PGPH) activity of the 20S proteasome. Proteolytic cleavage liberates the fluorescent 7-amino-4-methylcoumarin (AMC) reporter, enabling quantitative proteasome activity assays for research use.
- Fluorogenic substrate that releases 7-amino-4-methylcoumarin (AMC) upon cleavage.
- Designed to measure postacidic-like (PGPH) activity of the 20S proteasome.
- Reported purity 99.5%.
- Chemical formula C35H44N4O9.
- Molecular weight 664.75 g·mol⁻¹.
- White to off-white solid appearance.
- Available in multiple pack sizes including 50 mg.
- Storage: powder stable at -80°C for long-term and -20°C for short-term when sealed and protected from moisture.
Medchemexpress LLC HY-P1003 1mg Medchemexpress, Ac-DEVD-AMC CAS:169332-61-0 Purity:>98%
Medchemexpress, HY-P1003 1mg Ac-DEVD-AMC CAS:169332-61-0 Ac-DEVD-AMC is the Caspase-3 substrate . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Boc-Lys Ac-AMC 5mg
A fluorogenic HDAC substrate; ex/em = 340-360/440-460 nm, respectively; following deacetylation by an HDAC and trypsin cleavage, AMC is released and its fluorescence can be used to quantify HDAC activity