Isotopically Labeled Compounds
Medchemexpress LLC Rel-paroxetine-d4 hydrochloride | 1217683-35-6 | C19H17D4ClFNO3 | 1 MG
Rel-Paroxetine-d4 hydrochloride is an isotope-labeled rel-Paroxetine hydrochloride, intended for research use only. This compound serves as a tracer and an internal standard for quantitative analysis using methods such as NMR, GC-MS, or LC-MS.
- Utilized as a tracer for quantitation in drug development processes
- Functions as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS
- Contains stable heavy isotopes, potentially influencing pharmacokinetic and metabolic profiles of drugs
Cayman Chemical Lnsoprazole-d4 500ug
An internal standard for the quantification of lansoprazole by GC- or LC-MS
Medchemexpress LLC Clozapine-d8 | 1185053-50-2 | MFCD09752113 | 99.7% | 334.87 | C18H11D8ClN4 | 5 MG
Clozapine-d8 is the deuterium-labeled isotopologue of the antipsychotic clozapine, provided as a high-purity analytical standard for research use. It is intended as an internal standard for quantitative bioanalytical methods and preclinical studies where accurate measurement of clozapine is required.
- Deuterium-labeled internal standard for accurate quantitation.
- Suitable for LC-MS/MS and GC-MS analytical methods.
- High purity (≈99.7%).
- Provides improved assay precision and recovery.
- Supplied in small quantities appropriate for analytical standards.
Medchemexpress LLC Ac-Ala-OH-d3 | 1485548-36-4 | 134.15 | 5 MG
Ac-Ala-OH-d3 is presented as a white to off-white solid. This product has an isotopic enrichment of 99.8% and a purity of 99.0%, and is suitable for various research applications. It complies with given specifications.
- Appearance: White to off-white solid
- Purity: 99.0%
- Isotopic enrichment: 99.8%
- Tested and complies with specifications
- For research use only
Medchemexpress LLC Diphenylmethanol-d5 | 95450-78-5 | 189.26 | 5 MG
Diphenylmethanol-d5 is a deuterium labeled Diphenylmethanol, for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Deoxycholic acid sodium salt | 302-95-4 | 414.55 | 500 MG
Deoxycholic acid sodium salt is a bile acid, a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5. It is for research use only and not sold to patients.
- Activates G protein-coupled bile acid receptor TGR5
- High purity (99.89%)
- White to off-white solid appearance
- Suitable for research in intestinal metabolism and biological activity studies
- Stable at 4°C for solid form, and in solvent at -80°C or -20°C for extended periods
Medchemexpress LLC Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) | 2734410-01-4 | 151.14 | 1 MG
Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) is a 13C labeled Cinnamic acid, with potential use in cancer intervention. It has shown IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate, and lung carcinoma cells.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules as tracers for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Glutamine-13C5 | 184161-19-1 | MFCD00144603 | 151.11 | 5 MG
L-Glutamine-13C5 is the 13C-labeled L-Glutamine, a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. It provides a source of carbons for oxidation in some cells.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Non-essential amino acid.
- Involved in many metabolic processes.
- Provides a source of carbons for oxidation in some cells.
Medchemexpress LLC L-Tryptophan-α,β,β,2,4,5,6,7-d8 | 1233395-93-1 | 212.27 | 100 MG
L-Tryptophan-d8 is the deuterium-labeled L-Tryptophan. L-Tryptophan is an essential amino acid and a precursor of serotonin, melatonin, and vitamin B3.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Serine-d7 | 935275-35-7 | 112.14 | 100 MG
L-Serine-d7 is the deuterium-labeled form of L-Serine. L-Serine, a non-essential amino acid, plays a central role in cellular proliferation.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of elements like hydrogen and carbon.
- Deuterium substitution has potential to affect pharmacokinetic and metabolic profiles of drugs.
- High purity of 99.97%.
![Revvity Health Sciences Inc Glucagon, Receptor Grade, [<sup>125</sup>I]-, 10µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2397946.jpg-250.jpg)
Revvity Health Sciences Inc Glucagon, Receptor Grade, [125I]-, 10µCi
Glucagon, Receptor Grade, [125I]-, 10µCi
Medchemexpress LLC L-Threonine-d5 | 1217456-38-6 | CB71121697 | 124.15 | 5 MG
L-Threonine-d5 is the deuterium labeled L-Threonine, a natural amino acid produced by microbial fermentation and used in food, medicine, or feed applications. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers for quantitation during drug development, potentially influencing pharmacokinetic and metabolic profiles. This compound can serve as a tracer and an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Deuterium labeling can influence drug pharmacokinetics and metabolic profiles
- Produced by microbial fermentation
Medchemexpress LLC DL-Aspartic acid-d3 | 14341-75-4 | MFCD00144167 | 136.12 | 5 MG
DL-Aspartic acid-d3 is a deuterium labeled L-Aspartic acid. L-Aspartic acid is an amino acid capable of penetrating the blood-brain barrier. It is often utilized in the preparation of prodrugs designed to target colon and cecal tissues, and is commonly used in studies of inflammatory conditions.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ezetimibe-d4-1 (SCH 58235-d4-1) | 1093659-89-2 | 99.3% | 413.45 | 1 MG
Ezetimibe-d4-1 is deuterium labeled Ezetimibe, a potent cholesterol absorption inhibitor and a Niemann-Pick C1-like1 (NPC1L1) inhibitor. It also acts as a potent Nrf2 activator. This compound is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Endoxifen-d5 | 1185244-45-4 | 97.5% | 378.52 | 1 MG
Endoxifen-d5 is the deuterium labeled Endoxifen. Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.