Isotopically Labeled Compounds
Medchemexpress LLC Busulfan-d8 | 116653-28-2 | 99.7% | 1 MG
Busulfan-d8 is a deuterium labeled Busulfan, functioning as a potent alkylating antineoplastic agent. It causes DNA damage by cross-linking DNAs and DNA and proteins, inhibits thioredoxin reductase, and induces apoptosis. This compound acts as an immunosuppressive and myeloablative chemotherapeutic agent.
- Deuterium labeled compound
- Functions as a potent alkylating antineoplastic agent
- Causes DNA damage by cross-linking DNAs and DNA and proteins
- Inhibits thioredoxin reductase and induces apoptosis
- Acts as an immunosuppressive and myeloablative chemotherapeutic agent
- Can be used as a tracer for quantitation during drug development
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Thiamphenicol-d3 | 2211914-19-9 | 99.5% | 5 MG
Thiamphenicol-d3 is a deuterium labeled Thiamphenicol, a broad-spectrum antimicrobial antibiotic. It inhibits protein synthesis by binding to the 50S ribosomal subunit, resulting in a bacteriostatic effect against Gram-negative, Gram-positive aerobic, and anaerobic bacteria. This compound is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes of hydrogen, carbon, and other elements incorporated into the drug molecule
- Potential to affect the pharmacokinetic and metabolic profiles of drugs due to deuteration
Cayman Chemical LInoleIc AcId-d4 500ug
An internal standard for the quantification of linoleic acid by GC- or LC-MS
Medchemexpress LLC Acetylcholine-d9 bromide | 93449-32-2 | 98.9% | 1 MG
Acetylcholine-d9 (bromide) is the deuterium labeled Acetylcholine bromide.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Moricizine Hydrochloride | 29560-58-5 | 98.0% | 5 MG
Moricizine Hydrochloride (EN 313) is an orally active Class I antiarrhythmic agent. It works by decreasing the maximum rate of phase 0 depolarization, increasing the rates of phase 2 and 3 repolarization, and decreasing both the action potential duration and the effective refractory period.
- Orally active class I antiarrhythmic agent
- Decreases the maximum rate of phase 0 depolarization
- Increases rates of phase 2 and 3 repolarization
- Decreases action potential duration
- Decreases effective refractory period
- Target: Cytochrome P450
- Pathway: Metabolic enzyme/protease
Medchemexpress LLC Ranitidine-d6 hydrochloride | 1185238-09-8 | 97.0% | 1 MG
Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride (HY-B0281A). Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. It antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride also inhibits breast tumor development and spread in mice.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Target: H2 receptor.
Medchemexpress LLC Uridine-13C,15N2 | 369656-75-7 | 1 MG
Uridine-13C,15N2 is a 13C- and 15N-labeled Uridine. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention due to its potential to affect pharmacokinetic and metabolic profiles of drugs.
- Can be utilized as a tracer.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ethylmalonic acid-d5 | 66311-22-6 | 98.09% | 137.15 | 5 MG
Ethylmalonic acid-d5 | 66311-22-6 | 98.09% | 137.15 | 5 MG
Medchemexpress LLC Lenvatinib-d4 | 2264050-65-7 | 99.6% | 430.88 | 100 MG
Lenvatinib-d4 is a deuterium-labeled version of Lenvatinib. Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, demonstrating potent antitumor activities. Stable heavy isotopes like deuterium are incorporated into drug molecules, primarily as tracers for quantitation during drug development. Deuteration can also impact the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET.
Sigma Aldrich Fine Chemicals Biosciences Lauric-d23 acid >=98 atom % D, >=98% (CP) | 59154-43-7 | MFCD00144567 | 25MG
Lauric-d23 acid >=98 atom % D, >=98% (CP) | Purity: >=98% (CP) | Mol Wt: 223.46 | 59154-43-7 | MFCD00144567 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Dioctyl phthalate-3,4,5,6-d4 98 atom % D | 93952-13-7 | MFCD00144150 | 100MG
Dioctyl phthalate-3,4,5,6-d4 98 atom % D | Purity: 99% (CP) | Mol Wt: 394.58 | 93952-13-7 | MFCD00144150 | 100MG
Medchemexpress LLC Sucrose-13C | 99.5% | 343.29 g·mol⁻1 | C1113CH22O11 | 1mg
Sucrose-13C is 13C labeled Sucrose Sucrose (D-( )-Saccharose) is a disaccharide which is composed of two monosaccharides glucose and fructose Sucrose can be applied in some animal models including metabolic disease obesity diet on preference and diabetes et al[1]
Medchemexpress LLC 2-Iodoacetamide-d4 | 1219802-64-8 | 98.7% | 188.99 | 1 MG
2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide. 2-Iodoacetamide (Iodoacetamide) is an alkylating agent commonly used for alkylation of cysteine during sample preparation for proteomics. It is for research use only and not sold to patients. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation during drug development. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences Hexachlorobenzene-13C6 >=99 atom % 13C, 99% | 93952-14-8 | MFCD00144438 | 10MG
Hexachlorobenzene-13C6 >=99 atom % 13C, 99% | Purity: 99% | Mol Wt: 290.74 | 93952-14-8 | MFCD00144438 | 10MG