Isotopically Labeled Compounds
Medchemexpress LLC D-Glucose-13C-5 | 106032-62-6 | 98.0% | 100 MG
D-Glucose-13C-5 is the 13C labeled D-Glucose, a monosaccharide and important carbohydrate in biology. It acts as a carbohydrate sweetener, a vital component of general metabolism, and a critical signaling molecule involved in cellular metabolic status and biotic and abiotic stress responses.
- Functions as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Important carbohydrate in biological processes
- Acts as a carbohydrate sweetener
- Critical component in general metabolism
- Involved in cellular metabolic status signaling
- Participates in biotic and abiotic stress responses
Medchemexpress LLC Pimobendan-d3 | 74150-27-9 | 99.4% | 50 MG
Pimobendan-d3 (UD-CG115-d3) is deuterium labeled Pimobendan. It is a selective inhibitor of PDE3 with an IC50 of 0.32 μM. Deuterium labeled compounds are used as tracers for quantitation during drug development due to their potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
Medchemexpress LLC Norgestrel-d6 | 2376035-98-0 | 99.5% | 5 MG
Norgestrel-d6 is the deuterium labeled Levonorgestrel, a synthetic progestogen used as an active ingredient in some hormonal contraceptives. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It is intended for research use only and can serve as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled Levonorgestrel
- Synthetic progestogen
- Click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- For use as a tracer or internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical DesIpramIn-d4hydrochlorIde 1mg
An internal standard for the quantification of desipramine by GC- or LC-MS
Medchemexpress LLC Gemfibrozil-d6 | 1184986-45-5 | 98.7% | 5 MG
Gemfibrozil-d6 is a deuterium-labeled version of Gemfibrozil. Gemfibrozil acts as an activator of PPAR-α and is known as a lipid-lowering agent. It also functions as a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 reported as 5.8, 24, 69, and 82 μM, respectively.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Activator of PPAR-α
- Functions as a lipid-lowering agent
- Nonselective inhibitor of several P450 isoforms
Medchemexpress LLC Orlistat-d3 | 1356930-46-5 | 1 MG
Orlistat-d3 is a deuterated form of Orlistat, an irreversible inhibitor of pancreatic and gastric lipases and fatty acid synthase (FASN). It is employed in long-term research for obesity due to its anti-atherosclerotic effects, and can also be used as a tracer and internal standard for quantitative analysis.
- Used as a tracer in drug development.
- Functions as an internal standard for quantitative analysis, including by NMR, GC-MS, or LC-MS.
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs.
- Demonstrates anti-atherosclerotic effects.
- Shown to downregulate a repair protein in specific human cell lines during in vitro studies.
- Exhibits improved lipid profiles and increased antioxidant enzymes in in vivo studies.
Medchemexpress LLC Tiopronin-13C,d3 | 1189695-13-3 | 95.3% | 5 MG
Tiopronin-13C,d3 is deuterium labeled Tiopronin. It is intended for research use only and is not sold to patients.
- This compound can be used as a tracer
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC dGTP-d14 dilithium (2'-Deoxyguanosine-5'-triphosphate-d14 dilithium) | 2564-35-4 | 98.5% | 533.13 | 1 MG
dGTP-d14 (2'-Deoxyguanosine-5'-triphosphate-d14) dilithium is deuterium labeled dGTP. It is a guanosine nucleotide that can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides are highly susceptible to oxidative damage to 8-oxo-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Benzyl alcohol-d1 (Benzenemethanol-d1) | 14915-25-4 | 95.7% | 50 MG
Benzyl alcohol-d1, also known as Benzenemethanol-d1, is a deuterium-labeled analog of Benzyl alcohol, intended for research use only.
- Molecular weight of 109.14 and chemical formula of C7H7DO
- Appears as a colorless to light yellow liquid
- Incorporates stable heavy isotopes of hydrogen (deuterium)
- Soluble in DMSO (≥ 175 mg/mL), Ethanol (≥ 100 mg/mL), and water (20 mg/mL with ultrasonication)
- Serves as a tracer in scientific investigations
- Employed as an internal standard for quantitative analysis in techniques such as NMR, GC-MS, and LC-MS
Cambridge Isotope Laboratories CIS-5,8,11,14,17-EICOSAPENTAEN METHYL ESTER (19,19,20,20,20-D, 1 MG
CIS-5,8,11,14,17-EICOSAPENTAEN METHYL ESTER (19,19,20,20,20-D, 1 MG
Cambridge Isotope Laboratories L-TYROSINE (1-13C, 99%), 1 G, 81201-89-0
L-TYROSINE (1-13C, 99%), 1 G, 81201-89-0
Cambridge Isotope Laboratories PALMITIC ACID (D31, 98%), 1 G, 39756-30-4
PALMITIC ACID (D31, 98%), 1 G, 39756-30-4
Cambridge Isotope Laboratories CHLOROMETHANE-D3 (D, 99%), 1 L, 1111-89-3
CHLOROMETHANE-D3 (D, 99%), 1 L, 1111-89-3. **This item is shipped in a Code M lecture bottle. The fee for the bottle will need added to the order as a separate charge. Please include part# NC1539013 to the order.