Isotopically Labeled Compounds
Medchemexpress LLC Carfilzomib-d8 | 1537187-53-3 | 98.7% | 727.96 g/mol | C40H49D8N5O7 | 500 UG
Carfilzomib-d8 is a deuterium-labeled analog of carfilzomib, an irreversible proteasome inhibitor used in research. It serves as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS, and is suitable for studies of proteasome inhibition in cell models.
- Deuterium-labeled internal standard for quantitative mass spectrometry and NMR.
- Irreversible proteasome inhibitor activity; reported IC50 ≈ 5 nM in ANBL-6 and RPMI 8226 cells.
- Molecular formula C40H49D8N5O7; molecular weight 727.96 g/mol.
- Typical purity around 98.7% (batch dependent).
- Storage: protect from light; in solvent store at -80 °C up to 6 months, -20 °C up to 1 month.
Medchemexpress LLC Ponesimod-d7 100ug | 100UG
Ponesimod-d7 (ACT-128800-d7) is the deuterium-labeled Ponesimod (HY-10569) Ponesimod-d7 (ACT-128800) is a potent selective and orally active agonist of S1P1 with an IC50 of 6 nM in a radioligand binding assay Ponesimod-d7 activates S1P1-mediated signal transduction with high potency (EC50 5 7 nM) Ponesimod-d7 can protect against lymphocyte-mediated tissue inflammation[1 [2 [3
Medchemexpress LLC Carazolol-d7 | 1173021-02-7 | MFCD16652536 | >98.0% | 305.42 | C18H15D7N2O2 | 1 MG
Carazolol-d7 is the deuterium-labeled analogue of carazolol provided as a high-purity stable isotope standard for research and analytical applications. It is intended for use as an internal standard in quantitative mass spectrometry and for method development in pharmacology, ADME, and bioanalytical studies.
- Deuterium-labeled internal standard for LC-MS/MS and GC-MS assays.
- High chemical purity suitable for quantitative analysis.
- Characterized by molecular formula and molecular weight for accurate identification.
- Provided as a small, convenient pack size for trace-level applications.
- Suitable for pharmacokinetic and metabolism studies requiring isotopic standards.
Medchemexpress LLC 5-Methylcytosine-d4 | 1219795-15-9 | 129.15 | 5 MG
5-Methylcytosine-d4 is the deuterium labeled version of 5-Methylcytosine. 5-Methylcytosine is a known DNA modification in prokaryotes and eukaryotes. It forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and influences mRNA translation. It can be oxidized to produce 5hmC, 5fC, and 5caC. 5-Methylcytosine is used in epigenetics, developmental biology, and research on diseases such as colorectal cancer and hepatocellular carcinoma.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 25-Hydroxy VD2-d6 | 1262843-46-8 | C28H38D6O2 | 1 MG
25-Hydroxy VD2-d6 is the deuterium labeled 25-Hydroxy VD2.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Flurbiprofen-d5 | 215175-76-1 | MFCD27992097 | 99.8% | 249.29 g/mol | C15H8D5FO2 | 5 MG
Flurbiprofen-d5 is the deuterium-labeled isotopologue of flurbiprofen used as a stable isotope reference standard for analytical and mass spectrometry applications. It functions as an internal standard for quantitative LC-MS/MS assays and is provided in small, accurately weighed packages for method development and validation.
- Deuterated internal standard for LC-MS quantitation.
- High chemical purity: 99.8%.
- Molecular formula C15H8D5FO2 and molecular weight 249.29 g/mol.
- Supplied in small, calibrated quantities for accurate dosing.
- Suitable for method development, validation, and quantitative analysis.
Cayman Chemical NaphazolIn-d4hydrochlorIde 5mg
An internal standard for the quantification of naphazoline by GC- or LC-MS
Medchemexpress LLC Heptadecanoic acid-d33 | 352431-41-5 | 303.65 | 50 MG
Heptadecanoic acid-d33 is a deuterium labeled odd chain saturated fatty acid (OCS-FA). It is associated with several diseases, including coronary heart disease, prediabetes, type 2 diabetes, and multiple sclerosis. This product is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules as tracers
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Indole-13C | 85597-55-3 | 118.14 | 50 MG
Indole-13C is the 13C labeled Indole, an endogenous metabolite. It is intended for research use only and not for patient use. This compound serves as a tracer and internal standard for quantitative analysis in various analytical techniques.
- Used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotope of carbon
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Bexarotene-d4 | 2182068-00-2 | MFCD21363455 | 98.5% | 352.50 g/mol | C24H24D4O2 | 5 MG
Bexarotene-d4 is a deuterium-labeled analogue of bexarotene, a selective retinoid X receptor (RXR) agonist. Supplied as a purified solid for research use, it is commonly employed as an internal standard or tracer in LC-MS/GC-MS quantitation and metabolism studies involving bexarotene.
- Deuterium-labeled internal standard for mass spectrometry assays.
- High isotopic and chemical purity suitable for quantitative analysis.
- Stable solid form with recommended low-temperature storage.
- Used in pharmacokinetic, metabolism, and tracer studies.