Isotopically Labeled Compounds
Medchemexpress LLC Xylometazoline-d4 hydrochloride | 1218-35-5 | 1 MG
Xylometazoline-d4 hydrochloride is a deuterated form of Xylometazoline hydrochloride (HY-B0475). Xylometazoline hydrochloride acts as an α-adrenergic receptor agonist with a Ki ranging from 0.05 to 1.7 μM. It is known for its ability to constrict nasal blood vessels and consequently increase nasal airflow, making it suitable for research concerning nose stuffiness and runny nose.
- This compound serves as a tracer.
- It can be utilized as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
- Stable heavy isotopes, such as deuterium, are incorporated into drug molecules primarily for quantitation during the drug development process.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Flumequine-13C3 | 1185049-09-5 | 1 MG
Flumequine-13C3 is the 13C3 labeled Flumequine. It is a quinolone antibiotic that acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Applicable in isotope-labeled compounds research
- Suitable for metabolic flux analysis
- Used in therapeutic drug monitoring
Medchemexpress LLC Trospium-d8 chloride | 10405-02-4 | 1 MG
Trospium-d8 (chloride) is the deuterium-labeled form of Trospium chloride. Trospium chloride is an orally active, specific, and competitive antagonist of muscarinic cholinergic receptors (mAChRs), exhibiting antimuscarinic activity. It binds with high affinity to muscarinic receptors M1, M2, and M3, but not nicotinic cholinergic receptors.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporation of stable heavy isotopes can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7 | 1392208-04-6 | 99.6% | 1 MG
(Rac)-Ropivacaine-d7 is a stable isotope-labeled compound, identified as 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7. It appears as a white to off-white solid with an isotopic enrichment of 99.11%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.
- High purity of 99.6% (HPLC)
- Stable under recommended storage conditions
- Ideal for laboratory chemical applications and substance manufacturing
- For research use only
Medchemexpress LLC Sulfamethoxazole-d4 | 1020719-86-1 | MFCD03425632 | 98.2% | 257.30 g/mol | C10H7D4N3O3S | 10 MG
Sulfamethoxazole-d4 is a deuterium-labeled analogue of the sulfonamide antibiotic sulfamethoxazole, supplied as a high-purity powder for analytical and tracer applications. Intended as an isotope-labeled internal standard for quantitative LC-MS and related studies; molecular formula C10H7D4N3O3S, molecular weight 257.30 g/mol, CAS 1020719-86-1.
- Deuterium-labeled internal standard for quantitative LC-MS analysis.
- High purity suitable for LC-MS and other analytical methods.
- Powder form for easy dissolution and aliquoting.
- Stable under recommended storage conditions for long-term use.
- Applicable to studies of bacterial folate metabolism and related assays.
Medchemexpress LLC 3-Hydroxychrysene-d11 | 2468771-62-0 | C18HD11O | 1 MG
3-Hydroxychrysene-d11 is the deuterium labeled 3-Hydroxychrysene. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules serves as tracers for quantitation during drug development. Deuteration, in particular, has garnered attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled 3-hydroxychrysene
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Utilizes stable heavy isotopes for drug development quantitation
- Potential to influence pharmacokinetic and metabolic profiles
Cayman Chemical IloperIdon-d3 25mg
An internal standard for the quantification of iloperidone by GC- or LC-MS
Cayman Chemical FlonIcamId-15N 18O 1.2mL
An internal standard for the quantification of flonicamid by GC- or LC-MS
Medchemexpress LLC Guanfacine-13C,15N3 | 1189924-28-4 | 250.07 | 1 MG
Guanfacine-13C,15N3 is the 13C and 15N labeled version of Guanfacine. Guanfacine is an orally active noradrenergic α2A agonist that selectively targets the α2A receptor subtype. It has been observed to cause hypotension and sedation. This compound is used in research related to various prefrontal cortex (PFC) cognitive disorders, such as Tourette's syndrome and attention deficit hyperactivity disorder (ADHD). The incorporation of stable heavy isotopes into drug molecules, like in Guanfacine-13C,15N3, is primarily for quantitation during drug development, with deuteration specifically noted for its potential impact on pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Fumaric acid-d2 | 24461-32-3 | MFCD00144378 | 99.0% | 118.08 g/mol | C4H2D2O4 | 25 MG
Fumaric acid-d2 is the deuterium-labeled analog of fumaric acid used as a stable isotope standard and research reagent. It is supplied as a white to off-white solid with 99.0% purity and is intended for analytical, metabolic, and tracer studies. For research use only.
- Deuterium-labeled compound for tracer and analytical applications.
- High purity (99.0%) suitable for reference standards.
- Soluble in DMSO (≥ 100 mg/mL) for convenient stock preparation.
- Stable when stored as a powder at -20°C for long-term storage.
- Available in small mass sizes for analytical workflows.
Medchemexpress LLC Nonanedioic-d14 acid | 119176-67-9 | MFCD00068296 | 99.9% | 202.31 | C9H2D14O4 | 10 MG
Azelaic acid-d14 is the deuterium-labeled isotopologue of azelaic acid (nonanedioic acid), supplied as a high-purity solid for use as a stable-isotope internal standard and tracer in analytical chemistry and metabolic studies.
- High isotopic and chemical purity suitable for analytical standards.
- Supplied as a solid for accurate weighing and solution preparation.
- Batch-specific certificate of analysis provided for verification.
- Appropriate for use as an internal standard in LC-MS/MS and GC-MS methods.
- Available in small-mass packaging sizes for reference standard applications.
Apexbio Technology LLC Deoxycholic acid sodium salt 302-95-4 100mg
Deoxycholic acid sodium salt (CAS 302-95-4) is a bile acid derivative that functions as an endogenous ligand for the G protein-coupled bile acid receptor TGR5 Through activation of TGR5 it modulates intracellular signaling pathways and enzymatic activities thereby influencing diverse cellular processes This compound is widely utilized in biomedical research to investigate bile acid-mediated signaling mechanisms and their involvement in physiological and pathological conditions particularly those related to metabolic regulation and gastrointestinal diseases
![Revvity Health Sciences Inc ATP, [γ-<sup>32</sup>P]- 6000Ci/mmol 10mCi/ml , 250 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502809324.jpg-250.jpg)
Revvity Health Sciences Inc ATP, [γ-32P]- 6000Ci/mmol 10mCi/ml , 250 µCi
ATP, [γ-32P]- 6000Ci/mmol 10mCi/ml , 250 µCi
Cayman Chemical GalIc AcId-d2 10mg
An internal standard for the quantification of gallic acid by GC- or LC-MS
Medchemexpress LLC Levosulpiride-d3 | 124020-27-5 | 99.8% | 1 MG
Levosulpiride-d3 is the deuterium labeled Levosulpiride, an (S)-enantiomer of sulpiride that acts as a D2 receptor antagonist and atypical antipsychotic agent of the benzamide class. This compound is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.