COVID Testing Kits
Cayman Chemical SARSCoV2 SpIk Glycoprotin 50uL
A σ receptor ligand with anticancer and antiviral activites binds to σ1 and σ2 receptors (Kis 13 and 0.28 nM respectively in MCF-7 cell membranes) selective for σ1 and σ2 receptors over hERG channels (Ki 1000 nM) inhibits growth of MCF-7 and multidrug-resistant MCF-7/adr cells (IC50s 25 and 15 nM respectively) decreases basal P-gp levels in the same cells reduces SARS-CoV-2 infectivity in Vero E6 cells (IC90 278 nM)
Cayman Chemical SARSCoV2 SpIke GlycoproteIn
An inducer of ROS production induces lipid peroxidation increases in intracellular accumulation of ROS and decreases in the GSHGSSG ratio in MIA PaCa-2 pancreatic cancer cells from 0.5-10 UM cytotoxic to MIA PaCa-2 PANC-1 and BxPC-3 cancer cells (IC50s 0.64 0.34 and 0.9 UM respectively) acts synergistically with napabucasin to reduce colony formation in MIA PaCa-2 cells
Cayman Chemical SARS-CoV-2 Spike Glycoprotein
A phenylethanoid glycoside with diverse biological activities scavenges DPPH radicals in a cell-free assay and inhibits hydrogen peroxide-induced lipid peroxidation in V79-4 cells at 10 g/ml induces apoptosis and production of ROS in and reduces viability of OVCAR-3 cells from 7 5-30 M inhibits tumor growth in an OVCAR-3 mouse xenograft model at 30 mg/kg decreases brain amyloid deposition and increases exploratory behavior in AB42-infused rats at 2 5 and 5 mg/kg decreases xylene-induced ear edema in mice and increases survival in a mouse model of LPS-induced endotoxic shock
Cayman Chemical SARSCoV2 SpIke GlycoproteIn
A thymidylate synthase inhibitor (Ki 11 nM) inhibits cell growth in a panel of human and murine cancer cell lines (IC50s 0 39-6 6 M) inhibits the growth of L1210 cells an effect that is decreased by greater than 50-fold by the addition of exogenous thymidine induces cell cycle arrest at the S phase in L1210 cells at 0 7 and 3 5 M increases life span in a thymidine kinase-deficient L5178Y/TK- murine lymphoma model at 25-200 mg/kg
Cayman Chemical SARSCoV SpIke GlycoproteIn50uL
A steroid saponin with anticancer activity decreases proliferation of and apoptosis in MCF-7 and MDA-MB-231 cells (IC50s 5 and 2 5 UM respectively) disrupts the mitochondrial membrane potential activates caspase-3 and increases protein levels of PARP in HepG2 and R-HepG2 cells reduces tumor growth in an MCF-7 mouse xenograft model at 2 05 and 2 73 mg/kg for 10 days
Cayman Chemical SARSCoV2 nsp13 HelIcaseE 10ug
An FXR agonist (EC50 193 nM in a reporter assay) selective for FXR over the glucocorticoid androgen mineralocorticoid and progesterone receptors in HEK293 cells overexpressing the human receptors (EC50s 10 UM for all in a radioligand binding assay) increases the interaction between FXR and SRC-1 (EC50 121 nM in a cell-free assay) reduces plasma triglyceride and total cholesterol levels in LDL receptor-null mice (ED50s 3 4 and 2 mg/kg respectively) decreases plasma LDL and increases HDL levels in ZDF rats at 3 10 and 30 mg/kg for nine days
Epigentek Inc CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit (48 Assays)
For high throughput screening of compounds that inhibit the proprotein convertase cleavage of SARS-CoV-2
Creative Biomart Recombinant Influenza B virus B/Maryland/15/2016 Hemagglutinin Antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide