Lectins
Cayman Chemical Cholesteryl ArachIdate 500mg
A nucleoside analog converted intracellularly to 3-deazauridine triphosphate which inhibits the biosynthesis of CTP inhibits the growth of L1210 leukemia cells when used at a concentration of 6 UM dose-dependently reduces mortality in a mouse model of leukemia enhances the incorporation of decitabine into DNA in leukemia cells when used at a concentration of 20 UM reduces mortality when used at a dose of 100 or 150 mg/kg and combined with decitabine in a mouse model of leukemia
Cayman Chemical Cholesteryl Oleate 50mg
A MC4R antagonist (Ki 0.16 UM) selective for MC4R over MC3R and MC5R (IC50s 0.32 0.81 and 2.12 UM respectively) decreases cAMP production induced by [NDP]-a-MSH by 20 in MCR4-expressing HEK293 cell membranes but has no effect on cAMP levels in MC3R- or MC5R-expressing HEK293 cell membranes at 100 UM prevents the loss of lean body mass and enhances light-phase food consumption in a LLC mouse xenograft model but does not reduce tumor size at 15 mg/kg
Cayman Chemical Cholesteryl LIgnocerate 50mg
An antagonist of CCR9 (IC50 5.4 nM) selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s 10 UM for all) inhibits CCL25-induced Molt-4 chemotaxis in 0.1 BSA/HBSS and in 100 human AB serum (IC50s 3.5 and 33.4 nM respectively)
Cayman Chemical Cholesteryl Erucate 50mg
An internal standard for the quantification of dapagliflozin by GC- or LC-MS
Cayman Chemical Cholesteryl nrvonate 25mg
ABlactamase inhibitor (IC50s 8 80 and 38 nM for TEM-1 P99 and KPC-2Blactamases respectively) restores antimicrobial activity of ceftazidime ceftriaxone imipenem and piperacillin in vitro (MIC90 reduction 4-1024-fold across 190 E. coli and K. pneumoniae clinical isolates)
Cayman Chemical PalmItIc AcId13CC2 labeled 5mg
A macrolide anthelmintic lethal to C elegans (MAC 0 1 M) stimulates conductance in isolated shore crab muscle
Sigma Aldrich Fine Chemicals Biosciences Lectin from Bandeiraea sim2MG
Lectins are carbohydrate-binding proteins omnipresent found in fungi plants and animals. The structure of lectin is diversely studied in plants and animals. The secondary structure of this protein is rich in -strands and possesses carbohydrate binding sites on the surface.
Cayman Chemical Cholesteryl ArachIdonate 10mg
An alkaloid with diverse biological activities active against several strains of E histolytica amoebae (IC50s 0 73-10 22 g/ml) inhibits NF-KB signaling induced by TNF-a or IL-1B (IC50s 2 and 4 2 M respectively in a cell-basedBlactamase reporter assay) increases caspase-3/7 activity in ME180 cells (EC50 1 1 M) cytotoxic to HeLa cells reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s 0 46 and 0 5 M respectively) induces emesis in ferrets at 5 mg/kg an effect that can be prevented by ondansetron
Cayman Chemical Cholesteryl nrvonate 10mg
ABlactamase inhibitor (IC50s 8 80 and 38 nM for TEM-1 P99 and KPC-2Blactamases respectively) restores antimicrobial activity of ceftazidime ceftriaxone imipenem and piperacillin in vitro (MIC90 reduction 4-1024-fold across 190 E. coli and K. pneumoniae clinical isolates)
Cayman Chemical Cholesteryl Erucate 500mg
A potent and selective FTase inhibitor (IC50 21 nM) greater than 30-fold selective for FTase over GGTase (IC50 790 nM) prevents farnesylation of Ras inhibits proliferation of cells transformed by Ras farnesylation reduces GTP-Ras decreases angiographic vasospasm and improves clinical scores in a dog model of subarachnoid hemorrhage
Cayman Chemical ANTIBODY PHA-543613 50mg
A phospholipid has been used in the generation of LNPs for in vitro delivery of mRNA or nuclear-targeted plasmid DNA
Cayman Chemical ANTIBODY PHA-543613 5mg
Source Active recombinant mouse sPLA2 (Type X) expressed in E. coli Amino acids 29-151 MW 14.7 kDa