Cell Culture Media, Supplements, and Reagents
CPC Scientific H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH (trifluoroacetate salt) 1MG
EGFR fragment that contains the autophosphorylation site at Tyr992.ONE-LETTER SEQUENCE: DVVDADEYLIPQMOLECULAR FORMULA: C61H93N13O23MOLECULAR WEIGHT:1376.5STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [96249-43-3], RESEARCH AREA: CancerREFERENCES: A. Ullrich et al., Nature, 309, 418 (1984)
Apexbio Technology LLC Nateglinide 105816-04-4 10mg
Nateglinide (CAS 105816-04-4) is a synthetic oral antihyperglycemic agent classified within the meglitinide class It functions as an insulin secretagogue by selectively binding to pancreatic -cell ATP-dependent potassium channels resulting in membrane depolarization and subsequent stimulation of insulin release Nateglinide is widely employed in research focused on non-insulin-dependent diabetes mellitus providing a tool for investigating glucose-stimulated insulin secretion -cell responsiveness and the pharmacological modulation of insulinotropic pathways in metabolic disease models
eMolecules 105462-24-6 | Risedronic acid | MFCD00867080 | 1g
Ambeed | 1-Benzyl-3-iodo-1H-pyrrolo[23-b]pyridine | 250mg | 719807655 | A501449 | 1093759-51-3 | MFCD09834873 | 334.160 | C14H11IN2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Apexbio Technology LLC Chloroxine 773-76-2 50mg
Chloroxine (CAS 773-76-2) is a small-molecule agent that exerts antimicrobial antifungal and antiprotozoal activity by chelating metal ions essential for microbial proliferation thereby disrupting intracellular metal ion homeostasis and impairing critical metabolic pathways in pathogens Chloroxine demonstrates inhibitory activity with reported IC50 values typically ranging from submicromolar to low micromolar concentrations depending on the microorganism and assay conditions Based on these pharmacological properties chloroxine holds research potential in studies of intestinal amoebiasis pathogenesis experimental therapeutic evaluations and investigations of antifungal agents targeting fungi involved in dandruff and seborrheic dermatitis
Apexbio Technology LLC Cetylpyridinium Chloride 123-03-5 50mg
Cetylpyridinium chloride (CAS 123-03-5) is a small-molecule inhibitor targeting microbial cell membranes It is designed to disrupt bacterial lipid bilayers thereby altering membrane permeability and inhibiting microbial viability Cetylpyridinium chloride exerts its biological activity primarily through membrane destabilization via positively charged cetylpyridinium ions interacting with negatively charged microbial surfaces In in vitro studies cetylpyridinium chloride demonstrates inhibitory activity with IC50 values ranging approximately between 0 5 to 10 M depending on microbial strain type and experimental conditions Based on these pharmacological properties cetylpyridinium chloride holds research potential in evaluating oral microbial inhibition biofilm formation interference and cell membrane-targeted antibacterial strategies
Apexbio Technology LLC Oxybutynin chloride 1508-65-2 100mg
Oxybutynin chloride (CAS 1508-65-2) is a synthetic antimuscarinic agent that functions primarily by inhibiting the action of acetylcholine on muscarinic receptors in smooth muscle particularly within the bladder This antagonism results in reduced involuntary detrusor muscle contractions thereby modulating urinary urgency and frequency In biomedical research oxybutynin chloride is employed to investigate cholinergic pathways involved in bladder function neurogenic bladder disorders and the pharmacological modulation of muscarinic signaling in urinary physiology
Apexbio Technology LLC Ceftriaxone Sodium Trihydrate 104376-79-6 50mg
Ceftriaxone Sodium Trihydrate (104376-79-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby disrupting peptidoglycan cross-link formation and compromising bacterial cell wall biosynthesis Ceftriaxone Sodium Trihydrate exerts its biological activity primarily through inhibition of bacterial cell wall synthesis In in vitro studies Ceftriaxone Sodium Trihydrate demonstrates broad-spectrum antimicrobial inhibitory activity with reported IC50 values typically ranging from approximately 0 1 to 4 g/mL depending on the bacterial strain and experimental conditions Based on these pharmacological properties Ceftriaxone Sodium Trihydrate holds research potential in microbiological assays including susceptibility testing drug-resistance research and mechanistic studies involving bacterial PBPs
Apexbio Technology LLC Lomeguatrib 192441-08-0 10mg
Lomeguatrib (CAS 192441-08-0) is a potent inhibitor of O6-alkylguanine-DNA methyltransferase (MGMT) an enzyme involved in DNA repair that mitigates the cytotoxic effects of alkylating agents In MCF-7 cells Lomeguatrib inactivates MGMT with an approximate IC50 of 6 nM By suppressing MGMT activity Lomeguatrib sensitizes MGMT-expressing cell lines such as A375P and select mutBRAF and mutNRAS melanoma models to temozolomide but does not alter sensitivity to dacarbazine Clinical investigations have demonstrated dose-dependent inactivation of MGMT in patient-derived tumor tissues and peripheral blood mononuclear cells highlighting Lomeguatrib s value as a research tool for studying MGMT-mediated resistance mechanisms in cancer
Apexbio Technology LLC Thiamphenicol 15318-45-3 50mg
Thiamphenicol (CAS 15318-45-3) is a small-molecule inhibitor targeting the bacterial ribosomal 50S subunit It is designed to interfere with bacterial protein synthesis thereby regulating translational processes Thiamphenicol exerts its biological activity primarily through inhibition of peptide elongation by binding to the 50S ribosomal subunit In experimental studies Thiamphenicol demonstrates bacteriostatic activity with reported IC50 values for bacterial strains typically ranging from 0 5 8 g/mL depending on organism sensitivity growth conditions and assay methodologies Based on these pharmacological properties Thiamphenicol holds research potential in studying bacterial resistance mechanisms screening antibiotic candidates and investigating translation regulation in microbial systems
Apexbio Technology LLC Ciclopirox ethanolamine,50mg CAS# 41621-49-2
Ciclopirox ethanolamine, a broad-spectrum antifungal agent, inhibits dermatophytes and yeasts pathogenic with a minimal inhibitory concentration (MIC) of 0.98-3.9 μg/mL.Ciclopirox ethanolamine, working as an iron chelator, suppresses a substantial number of clinically relevant dermatophytes, yeasts, and molds, including the frequently azole-resistant Candida species Candida glabrata, Candida krusei, and Candida guilliermondii. Moreover, Ciclopirox has been proved to inhibit a wide range of bacteria in humans, including many gram-positive and gram-negative species pathogenic bacteria. [1] Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC HY-P7370 10ug Medchemexpress, IL-12 (CHO-expressed), Rat CAS: Purity:>98%
Medchemexpress, HY-P7370 10ug IL-12 (CHO-expressed), Rat CAS: Recombinant Rat Interleukin-12 (CHO-expressed) is an inflammatory cytokine that promotes the response of the immune system. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.