Laboratory Specialty Services
Apexbio Technology LLC SGI-1027 1020149-73-8 10mg
SGI-1027 (CAS 1020149-73-8) is a small-molecule inhibitor of DNA methyltransferases (DNMTs) exhibiting IC50 values of 12 5 M for DNMT1 8 M for DNMT3A and 7 5 M for DNMT3B It acts by competitively inhibiting the cofactor Ado-Met binding site rather than the DNA substrate site resulting in reduced DNMT activity and subsequent inhibition of DNA methylation SGI-1027 suppresses both mammalian and bacterial DNMTs affecting endogenous and recombinant forms In cancer cell models it induces demethylation of CpG islands in gene promoter regions leading to reactivation of silenced tumor suppressor genes such as P16 and TIMP3 and promotes DNMT1 degradation via the proteasome pathway SGI-1027 is utilized in epigenetics research to study DNA methylation dynamics and gene reactivation
Medchemexpress LLC Isoeugenol | 97-54-1 | 164.20 | 1 ML
Isoeugenol is an essential oil constituent of nutmeg, clove, and cinnamon. It inhibits the growth of Escherichia coli and Listeria innocua with MICs of 0.6 mg/mL and 1 mg/mL, respectively. Its antibacterial activity covers a broad range of Gram-positive and Gram-negative bacteria. Isoeugenol has a non-disruptive detergent-like mechanism of action.
- Essential oil constituent
- Inhibits growth of Escherichia coli and Listeria innocua
- Broad-spectrum antibacterial activity
- Non-disruptive detergent-like mechanism of action
Hampton Research NATRIX NO11 185ML
HR2-918-11/Natrix #11 (A11), 185 ml - 0.01 M Magnesium chloride hexahydrate, 0.05 M Sodium cacodylate trihydrate pH 6.0, 1.0 M Lithium sulfate monohydrate. Please note items from this supplier are non-returnable.
Hampton Research NATRIX NO17 185ML
HR2-918-17/Natrix #17 (B5), 185 ml - 0.2 M Potassium chloride, 0.01 M Calcium chloride dihydrate, 0.05 M Sodium cacodylate trihydrate pH 6.0, 10 % w/v Polyethylene glycol 4,000. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO04 185ML
HR2-920-04/MembFac #04 (A4), 185 ml - 0.1 M Sodium chloride, 0.1 M Sodium acetate trihydrate pH 4.6, 12% v/v 2-Propanol. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO06 185ML
HR2-920-06/MembFac #06 (A6), 185 ml - 0.1 M Sodium acetate trihydrate pH 4.6, 1.0 M Ammonium sulfate. Please note items from this supplier are non-returnable.
Hampton Research HR2-926-A3/Grid Screen PEG 6000 #A3, 185 ml - 0.1 M MES monohydrate pH 6.0, 5% w/v Polyethylene glycol 6,000
HR2-926-A3/Grid Screen PEG 6000 #A3, 185 ml - 0.1 M MES monohydrate pH 6.0, 5% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
Hampton Research HR2-926-D6/Grid Screen PEG 6000 #D6, 185 ml - 0.1 M BICINE pH 9.0, 30% w/v Polyethylene glycol 6,000
HR2-926-D6/Grid Screen PEG 6000 #D6, 185 ml - 0.1 M BICINE pH 9.0, 30% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
Hampton Research HR2-928-B5/Grid Screen PEG/LiCl #B5, 185 ml - 0.1 M Tris pH 8.0, 1.0 M Lithium chloride, 10% w/v Polyethylene glycol 6,000
HR2-928-B5/Grid Screen PEG/LiCl #B5, 185 ml - 0.1 M Tris pH 8.0, 1.0 M Lithium chloride, 10% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
Cell Signaling Technology SB203580, p38 MAPK Inhibitor, 5 mg
SB203580 is a selective and potent inhibitor of p38 MAP kinase that functions by binding to the ATP-binding pocket of the enzyme. It effectively inhibits the catalytic activity of p38 MAPK, thereby preventing the activation of downstream MAPKAPK-2 and the subsequent phosphorylation of HSP27. This compound is a useful tool for studying signaling pathways involved in cellular responses to cytokines and stress.
- Selective inhibition of p38 MAPK catalytic activity
- Does not significantly inhibit p44/42 MAPK or SAPK/JNK
- Supplied as a lyophilized white powder for reconstitution in DMSO
- Suitable for in vitro research applications
- Molecular weight of 377.4 g/mol
- High purity (≥98%)
Hampton Research HR2-928-C6/Grid Screen PEG/LiCl #C6, 185 ml - 0.1 M BICINE pH 9.0, 1.0 M Lithium chloride, 20% w/v Polyethylene glycol 6,000
HR2-928-C6/Grid Screen PEG/LiCl #C6, 185 ml - 0.1 M BICINE pH 9.0, 1.0 M Lithium chloride, 20% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
Hampton Research HR2-939-19/StockOptions Sodium Cacodylate #19 pH 6.9, 185 ml
HR2-939-19/StockOptions Sodium Cacodylate #19 pH 6.9, 185 ml. Please note items from this supplier are non-returnable.
Crescent Chemical Co Inc SERVALYT™ 5-7
SERVALYT™ 5-7 40 % (w/v) solution in water SERVALYT™ Carrier Ampholytes (40 % w/v in water). Standard quality (analytical grade) for general use in IEF. Size - 10ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42905.01
Crescent Chemical Co Inc SERVALYT™ 3-10 ISO-DALT
SERVALYT™ 3-10 Iso-Dalt 40 % (w/v) solution in water Iso-Dalt quality; special 2D grade to be used in 2D electrophoresis. Size - 2ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42951.04
Kyfora Bio Polyethylenimine Hydrochloride, Linear MW 160,000 (LPEI 160k) 2GR
L-PEI 160K is a highly-charged linear cationic polymer that readily binds highly anionic substrates. In research, LPEI 160k can be used to make composites for CO2 sensing. Key application(s): CO2 sensing