Laboratory Specialty Services
Apexbio Technology LLC DiscoveryProbe™ Apoptosis Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Apoptosis Compound Library consists of 643 apoptosis-associated small molecules widely documented in scientific literature and approved by authoritative institutions including FDA The library targets key proteins involved in apoptosis signaling pathways such as caspases MDM2 TNF- and p53 facilitating comprehensive studies into programmed cell death mechanisms and related pathological conditions Representative compounds in this collection include selective caspase modulators TNF- pathway inhibitors and MDM2-p53 interaction agents Researchers can leverage this specialized library for apoptosis-focused drug screening mechanistic pathway exploration and therapeutic candidate identification in disease models characterized by apoptosis dysregulation
Apexbio Technology LLC DiscoveryProbe™ Anti-diabetic Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
The DiscoveryProbe Anti-diabetic Compound Library comprises 110 small-molecule compounds including FDA-approved agents designed for diabetes-related biomedical research This collection targets metabolic regulatory pathways involved in diabetes such as dipeptidyl peptidase-4 (DPP-4) sodium-glucose co-transporter (SGLT) poly (ADP-ribose) polymerase (PARP) and ATP-sensitive potassium channels Representative compounds include metformin glibenclamide empagliflozin rosiglitazone and sitagliptin This library serves as a resource for investigating the molecular mechanisms of diabetes conducting potential therapeutic screening studies and developing novel diabetes-relevant research models
Apexbio Technology LLC DiscoveryProbe™ Ion Channel Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Ion Channel Compound Library comprises 199 compounds with defined activities targeting various ion channels These channels include NMDA receptors P2X purinergic receptors TRPV1 channels AMPA receptors ATPases and TRP channels Selected compounds have documented biological activities validated by publications and recognized approvals by FDA EMA or other authoritative institutions Representative compounds such as channel antagonists and agonists facilitate mechanistic ion channel studies and pharmacological validation The library is optimized for high-throughput screening (HTS) and high-content screening (HCS) serving as a tool for exploring ion channel modulation mechanism determination target identification and functional assays in biomedical research
Frontier Specialty Chemicals 100MG DEUTEROPORPHYRIN IX DIHY
Deuteroporphyrin IX dihydrochloride; CAS: 68929-05-5; 100mg
TARGETMOL CHEMICALS INC SGI-1027 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1 DNMT3A and DNMT3B are 6 8 7.5 uM respectively. purity: 99%
Apexbio Technology LLC DiscoveryProbe™ Ubiquitination Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Ubiquitination Compound Library comprises 144 small molecules curated specifically for investigating ubiquitination signaling pathways These compounds engage targets such as proteasomes mTOR inhibitor of apoptosis proteins (IAPs) deubiquitinating enzymes (DUBs) and PI3K among others Provided either as lyophilized powders or dissolved in DMSO solutions the library facilitates studies examining enzyme modulation and ubiquitin-mediated protein regulation Representative molecules in this collection include proteasome inhibitors IAP antagonists and DUB modulators Applicable in cellular assays drug screening and target validation experiments the library supports fundamental biomedical research approved for use in laboratory settings
Crescent Chemical Co Inc SERVALYT™ 5-7
SERVALYT™ 5-7 40 % (w/v) solution in water SERVALYT™ Carrier Ampholytes (40 % w/v in water). Standard quality (analytical grade) for general use in IEF. Size - 10ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42905.01
Apexbio Technology LLC DiscoveryProbe™ Immunology/Inflammation Compound Library Plus 100uL/well(10 mM solution),96 Well Deep Well Plate
The DiscoveryProbe Immunology/Inflammation Compound Library comprises 295 bioactive small molecules approved by regulatory bodies such as FDA and EMA or validated through peer-reviewed publications Designed specifically for biomedical research this library targets immune and inflammatory response pathways through modulation of relevant enzymes and signaling proteins including PDE IRAK TLR COX and related pathways Representative agents in this collection include known modulators such as celecoxib (COX inhibitor) roflumilast (PDE inhibitor) and IRAK inhibitor compounds This carefully curated collection provides an essential toolkit for investigating regulatory mechanisms compound screening assays target validation and drug discovery studies in inflammation and immunological disorders
Medchemexpress LLC Compound E | 209986-17-4 | 99.97% | C27H24F2N4O3 | 1 ML
Compound E is a γ-secretase inhibitor. It blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage, making it suitable for various research applications.
- Blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage
- Inhibits gamma secretase-mediated amyloid beta (1 to 40) production
- Reduces proliferation of T47D and MCF-7 cell lines
STA PHARMACEUTICAL US LLC 2'-OMe C(Ac) amidite | 1 g | CAS 199593-09-4 | MDL MFCD12912403
2'-OMe C(Ac) amidite is a Amidite reagent (Subcategory: 2'-OMe Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 199593-09-4
- MDL: MFCD12912403
- InChIKey: WNWUMIPFLOKTEZ-UAQIPLLRSA-N
- Molecular Weight: 801.877761998
- Molecular Formula: C42H52N5O9P
- Purity: ≥99%
- Container Type: 30 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 47.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C=C2)NC(C)=O)=O)O[C@@H]1COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OC)OCCC#N)C(C)C)C
STA PHARMACEUTICAL US LLC 2'-OMe C(Ac) amidite | 25 g | CAS 199593-09-4 | MDL MFCD12912403
2'-OMe C(Ac) amidite is a Amidite reagent (Subcategory: 2'-OMe Series) sold by WuXi TIDES. Offered in 25 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 199593-09-4
- MDL: MFCD12912403
- InChIKey: WNWUMIPFLOKTEZ-UAQIPLLRSA-N
- Molecular Weight: 801.877761998
- Molecular Formula: C42H52N5O9P
- Purity: ≥99%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C=C2)NC(C)=O)=O)O[C@@H]1COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OC)OCCC#N)C(C)C)C
Apexbio Technology LLC DiscoveryProbe™ Anti-Virus Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
The DiscoveryProbe Anti-Virus Compound Library comprises 509 structurally diverse antiviral small molecules including FDA-approved agents and preclinical research compounds Designed specifically for antiviral research in biomedical laboratories this collection covers various mechanisms of action targeting viral enzymes such as HCV protease NS3/4a protease and host-directed targets such as MEK1/2 kinases Representative compounds include protease inhibitors and kinase-pathway modulators employed clinically or in advanced experimental stages This library serves as a resource to investigate virus-host interactions antiviral efficacy studies mechanism analyses and candidate compound screenings in virology and drug discovery
Medchemexpress LLC cis-Isoeugenol | 5912-86-7 | 164.20 | 100 MG
cis-Isoeugenol is the cis isomer of Isoeugenol. It is for research use only and not sold to patients.
- Liquid appearance
- Colorless to light yellow
- Classified as phenol and monophenol
- Initially sourced from plants
- Purity of 95.0%
- Soluble in DMSO at 100 mg/mL
- Store pure form at -20°C for 3 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Crescent Chemical Co Inc SERVALYT™ 3-5
SERVALYT™ 3-5 40 % (w/v) solution in water SERVALYT™ Carrier Ampholytes (40 % w/v in water). Standard quality (analytical grade) for general use in IEF. Size - 10ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42903.01