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Laboratory specialty services comprise a range of services, including, but not limited to, analytical testing services for pharmaceutical, biomedical, and other life sciences laboratories.
HR2-928-D3/Grid Screen PEG/LiCl #D3, 185 ml - 0.1 M MES monohydrate pH 6.0, 1.0 M Lithium chloride, 30% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
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HR2-920-48/MembFac #48 (D12), 185 ml - 0.1 M Sodium citrate tribasic dihydrate, 0.1 M TRIS hydrochloride pH 8.5, 5% v/v Polyethylene glycol 400. Please note items from this supplier are non-returnable.
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HR2-944-40/Index #40 (D4), 185 ml - 0.1 M Citric acid pH 3.5, 25% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
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HR2-920-15/MembFac #15 (B3), 185 ml - 0.1 M Sodium chloride, 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 12% v/v (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.
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HR2-920-38/MembFac #38 (D2), 185 ml - 0.6 M Magnesium sulfate hydrate, 0.1 M HEPES sodium pH 7.5, 4% v/v (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.
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2'-OMe C(Ac) amidite is a Amidite reagent (Subcategory: 2'-OMe Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications - CAS: 199593-09-4 - MDL: MFCD12912403 - InChIKey: WNWUMIPFLOKTEZ-UAQIPLLRSA-N - Molecular Weight: 801.877761998 - Molecular Formula: C42H52N5O9P - Purity: ≥99% - Container Type: 250 mL Glass (28-400) - Pack Size: 10 g - Net Weight: 10 g - Gross Weight: 179.7 g - Commodity Code: 29349990 - Country Of Origin: China - IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C=C2)NC(C)=O)=O)O[C@@H]1COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OC)OCCC#N)C(C)C)C
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
TAK-285 is a potent, selective, ATP-competitive, orally active inhibitor of HER2 and EGFR (HER1) used in oncology and kinase research. It exhibits low-nanomolar potency against HER2 and EGFR, shows selectivity over related kinases, and has demonstrated antitumor activity with the ability to cross the blood-brain barrier.
Potent ATP-competitive inhibitor of HER2 and EGFR with low-nanomolar IC50 values.
Greater than 10-fold selectivity for HER1/2 compared with HER4.
Demonstrated antitumor activity and ability to penetrate the blood-brain barrier.
High purity suitable for biochemical and cellular assays.
Available as solid packs and as a 10 mM solution in DMSO for stock preparation.
Well characterized by molecular formula and molecular weight for compound verification.
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