Immunosuppressant Drug Testing Controls and Calibrators
Immunosuppressant Drug Testing Controls and Calibrators
Thermo Scientific™ QMS™ Tacrolimus Immunoassays and Calibrators
Achieve excellent low-end precision and sensitivity with the Thermo Scientific™ QMS™ Tacrolimus Immunoassay.
Thermo Scientific™ QMS™ Therapeutic Drug Monitoring (TDM) Calibrators
Accurately measure therapeutic drug levels in serum and plasma with Thermo Scientific™ QMS™ TDM Calibrators, offered in Levels A to F.
Thermo Scientific™ CEDIA™ Mycophenolic Acid Immunoassays, Calibrators and Controls
Complete your ISD panel with the Thermo Scientific™ CEDIA™ Mycophenolic Acid Immunoassay.
Thermo Scientific™ QMS™ Therapeutic Drug Monitoring (TDM) Controls
Ensure accurate results when testing with the newest TDM reagents with Thermo Scientific™ QMS™ TDM Controls, offered in three levels.
Thermo Scientific™ QMS™ Everolimus Immunoassays, Calibrators and Controls
Obtain results you can count on for immunosuppressant drug monitoring with the Thermo Scientific™ QMS™ Everolimus Immunoassay.
Thermo Scientific™ CEDIA™ Therapeutic Drug Monitoring (TDM) Calibrators
Save time while maintaining accuracy with economical Thermo Scientific™ CEDIA™ Therapeutic Drug Monitoring (TDM) Calibrators, optimized for use with CEDIA TDM Assays.
AdipoGen Everolimus
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that shows improved pharmacokinetics and pharmacodynamics. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Since mTORC2 is believed to play an important role in glucose metabolism and the immune system, selective inhibition of mTORC1 achieves many of the benefits of rapamycin without the associated glucose intolerance and immunosuppression Anticancer agent.
AdipoGen Everolimus
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that shows improved pharmacokinetics and pharmacodynamics. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Since mTORC2 is believed to play an important role in glucose metabolism and the immune system, selective inhibition of mTORC1 achieves many of the benefits of rapamycin without the associated glucose intolerance and immunosuppression Anticancer agent.
Cayman Chemical EverolImus-d4 1mg
A quinolone antibiotic active against Gram-positive and Gram-negative bacteria including S aureus and E coli (MICs 10 and 1 Ug/ml respectively) inhibits growth of nalidixic acid-sensitive strains of E coli in an in vitro model of bacterial cystitis at 10 and 50 mg/L active against chloroquine-sensitive and -resistant strains of P falciparum in vitro (IC50s 41 4 and 14 4 Ug/ml respectively) and against hepatic stages of P yoelii yoelii (IC50 21 6 Ug/ml)
AdipoGen Everolimus
Chemical. CAS 159351-69-6. Formula C53H83NO14. MW 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 FKBP-12 to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin mTOR. More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo.
Diapharma Group, Inc. Technothrombin Thrombin Generation Assay (TGA) Control – Low, 5 x 1 mL
Technothrombin TGA (Thrombin Generation Assay) Control Low. Human plasma with decreased thrombin generation, lyophilized.
