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Thermo Scientific™ Lab Vision™ GRP94, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ GRP94, Rabbit Polyclonal Antibody.

Specifications

Antigen GRP94
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Host Species Rabbit
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Products 5
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
RB10642P
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Thermo Scientific™
RB10642P
Purified Ab with BSA and Azide 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
RB10642R1
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Thermo Scientific™
RB10642R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
RB10642P0
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Thermo Scientific™
RB10642P0
Purified Ab with BSA and Azide 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
RB10642P1
View Documents
Thermo Scientific™
RB10642P1
Purified Ab with BSA and Azide 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
RB10642R7
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Thermo Scientific™
RB10642R7
Ready-to-use for IHC (UVLP) 7mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ GRP94, Rabbit Polyclonal Antibody.

Heat shock protein (HSP) molecular chaperones are environmental stress inducible gene products. The human HSP 90 family consists of 17 genes classified into four classes: HSP90AA, HSP90AB, HSP90B and TRAP. HSP 90 family members guide the normal folding, intracellular disposition and proteolytic turnover of many key regulators of cell growth, differentiation and survival. GRP 94, glucose regulated protein 94 kDa, a HSP90 family member, (also known as tumor rejection antigen 1 (TRA1), ECGP and GP96), localizes to the ER, is highly expressed in BGC-823 human gastric carcinoma cells and is upregulated in human endothelial cells in response to hypoxia by HIF-1. TRAP1 (TNF receptor-associated protein 1), also designated HSP 75 is a mitochondrial matrix component that plays a role in the induction of apoptosis in response to reactive oxygen species.

Host Species: Rabbit

Species Reactivity: Human. Others not known.

Epitope: C-terminal

Immunogen: Synthetic peptide corresponding to C-terminal of human GRP94

Molecular Weight: 94 kDa

Positive Control: Breast CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

GRP94
Polyclonal
Rabbit
Cancer and Tumor Biology
Synthetic peptide corresponding to C-terminal of human GRP94
Immunohistochemistry (Paraffin)
Unconjugated
RUO
Primary
Breast CA
SDS
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