Precipio™ HemeScreen MPN Panels

The HemeScreen MPN Panel-4 is an RUO pre-plated kit used to detect MPN-related gene mutations for JAK2, MPL, and CALR genes through HRM methods.

Catalog Number	Mfr. No.	Quantity
22-021-968	Precipio™ HS4PMPN	4 Samples
22-021-969	Precipio™ HS8PMPN	8 Samples

Description

HemeScreen is a proprietary set of RUO (Research Use Only) reagents used to screen the wild type (Negative) from Mutated (Positive) genes in a simplified workflow relative to alternative molecular testing technologies (RT-PCR or NGS).

• Pre-plated configuration with embedded mutant, wild type, and NTC controls to run 4 or 8 samples in duplicate
• Simplified workflow and reduced chance of error
• Data capture during thermocycling
• Fast turnaround time
• Broad mutation detection (SNPs, Modifications, Indels)
• Low limits of detection
• Results are qualitative and DNA sequencing is required to identify specific isoforms
• LOD: 5%
• Assay includes Primers-Mastermix Mix and controls
• Requires HRM-enabled RT-PCR (example Thermo Fisher™ Quantstudio 3 or higher)

Specifications

• Content And Storage: 96-well Plate with Gene Targets, Positive, Negative, and Wild Type Controls. Store at -20°C
• For Use With (Equipment): PCR Instruments
• Sensitivity: 0.95
• Target: JAK2 Ex. 14 (V617F), JAK2 Ex. 12, JAK2 Ex. 13, MPL, CALR

• Detection Method: HRM
• Includes Label or Dye: Yes
• Shipping Condition: Dry Ice
• Target Specificity: >99%

Safety and Handling

ShelfLife : 1 Year