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Epidermal Growth Factor Receptor/EGFR Ab-10 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

$297.00 - $984.00

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-10
Clone 111.6
Applications Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Host Species Mouse
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Products 7
Catalog Number Mfr. No. Form Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Conjugate Quantity Price Quantity & Availability  
MS378B0
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Epredia
MS378B0
Concentrated Biotin 100 μL
Each for $297.00
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MS378B1
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Epredia
MS378B1
Concentrated Biotin 500 μL
Each for $984.00
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MS378P1
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Epredia
MS378P1
Concentrated Unconjugated 500 μL
Each for $789.00
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MS378P0
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Epredia
MS378P0
Concentrated Unconjugated 100 μL N/A N/A N/A
MS378P1ABX
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Epredia
MS378P1ABX
Concentrated Unconjugated 100 μL N/A N/A N/A
MS378PABX
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Epredia
MS378PABX
Concentrated Unconjugated 200 μL N/A N/A N/A
MS378R1
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Epredia
MS378R1
Prediluted Unconjugated 1 mL N/A N/A N/A
Description

Description

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 111.6

Isotype: IgG1

Species Reactivity: Human. Not mouse and rat.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells; Skin, Placenta or Squamous cell CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native only)
  • Effect on EGF Binding (Inhibitory)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Epidermal Growth Factor Receptor/EGFR Ab-10
Immunohistochemistry (Paraffin), Immunoprecipitation
Mouse
EGFR Family
Extracellular domain of human recombinant EGFR protein
Primary
111.6
Monoclonal
RUO
Human
IgG1
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