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Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.

Specifications

Antigen Estrogen Receptor (SP1)
Clone SP1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Host Species Rabbit
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Products 5
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
RM9101S0
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Epredia
RM9101S0
Concentrated 100 μL N/A N/A N/A
RM9101S1
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Epredia
RM9101S1
Concentrated 500 μL N/A N/A N/A
RM9101S
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Epredia
RM9101S
Concentrated 1 mL N/A N/A N/A
RM9101R7
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Epredia
RM9101R7
Prediluted 7 mL N/A N/A N/A
RM9101RQ
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Epredia
RM9101RQ
Ready-to-Use 12 mL N/A N/A N/A
Description

Description

Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Clone: SP1

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor

Molecular Weight: 67 kDa

Positive Control: Breast CA, MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence (Not verified)
  • Flow Cytometery (Not verified)

Specifications

Specifications

Estrogen Receptor (SP1)
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Rabbit
Steroids Hormones and Growth Factors
Primary
SP1
Monoclonal
IVD
Synthetic peptide derived from C-terminal of human estrogen receptor
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