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HER-2/c-erbB-2/neu Ab-4 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

$179.00 - $1003.00

Specifications

Antigen HER-2/c-erbB-2/neu Ab-4
Clone N12
Applications Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Format Concentrated
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Products 8
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS301B
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Epredia
MS301B
200μg/mL Biotin 1mL
Each for $1,003.00
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MS301B1
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Epredia
MS301B1
200μg/mL Biotin 500μL
Each for $660.00
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MS301P
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Epredia
MS301P
200μg/mL Unconjugated 1mL
Each for $788.00
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MS301P0
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Epredia
MS301P0
200μg/mL Unconjugated 100μL
Each for $179.00
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MS301P1
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Epredia
MS301P1
200μg/mL Unconjugated 500μL
Each for $502.00
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MS301B0
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Epredia
MS301B0
200μg/mL Biotin 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS301P1ABX
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Epredia
MS301P1ABX
1mg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS301PABX
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Epredia
MS301PABX
1mg/mL Unconjugated 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: N12

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Inhibits Tumor Growth (∽90%)
  • Inhibits Cell Proliferation
  • Effect on HER-2 Internalization (Moderate)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

HER-2/c-erbB-2/neu Ab-4
Immunofluorescence, Immunohistochemistry (Frozen)
Concentrated
RUO
Primary
IgG1
N12
Monoclonal
Mouse
EGFR Family
Intact SKBR-3 breast cancer cells
SDS
Product Certifications
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