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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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D-I03 is a small-molecule selective RAD52 inhibitor used as a research reagent to study RAD52-dependent single-strand annealing and D-loop formation. It shows cellular activity against BRCA1- and BRCA2-deficient cells.
Selective RAD52 inhibitor with Kd 25.8 μM.
Inhibits RAD52-dependent single-strand annealing and D-loop formation.
Cellular activity: suppresses growth of BRCA1- and BRCA2-deficient cells.
Reported IC50 values: 5 μM (SSA) and 8 μM (D-loop).
Purity 99.7%.
Molecular weight 428.64 g/mol; formula C23H36N6S.
Physical state solid; color off-white to light yellow.
Solubility in DMSO 50 mg/mL.
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Isopropyl-b-D-thiogalactopyranoside (IPTG) research grade, dioxane-free Analog of galactose, not split by β-galactosidase. Inducer of the lac operon in bacteria. Used in conjunction with X-Gal(5-bromo-4-chloro-indolyl-β-D-galactoside, cat. no. 15243) for detection of lac+ colonies. Dissolv
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KI696 isomer is the less active stereoisomer of KI696, a high-affinity probe that disrupts the Keap1-NRF2 interaction. Supplied as a white to off-white solid for research use, it is offered in solid and DMSO solution formats; follow recommended storage conditions for stability.
Less active stereoisomer that disrupts the Keap1-NRF2 interaction.
High purity (99.3%).
White to off-white solid physical form.
Molecular formula C28H30N4O6S; molecular weight 550.63.
Available as solids and 10 mM solutions in DMSO.
Store powder at -20°C and solutions at -80°C for long-term stability.
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