Carbohydrates
Medchemexpress LLC Garcinone D | 107390-08-9 | 10 MM 1 ML
Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 (IC50 for CDK2/CyclinE1 is 28.23 μM). It promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression, and enhancing the Nrf2/HO-1 signaling pathway. Additionally, it blocks the tumor cell cycle by inhibiting CDK2/CyclinE1 and can inhibit prostate and breast cancer.
- Activator of STAT3/Cyclin D1 and Nrf2/HO-1 pathways
- Inhibitor of CDK2/CyclinE1
- Promotes neural stem cell proliferation
- Blocks tumor cell cycle
- Regulates C17.2 neural stem cell viability
- Promotes G1-S phase transition and arrests cell cycle in S phase in C17.2 neural stem cells
- Increases p-STAT3, Cyclin D1, Nrf2, and HO-1 proteins in C17.2 neural stem cells
Medchemexpress LLC 4-Nitrophenyl 4-guanidinobenzoate hydrochloride | 19135-17-2 | 99.4% | 336.73 | 1 ML
This product, 4-Nitrophenyl 4-guanidinobenzoate (NPGB) hydrochloride, is a potent sperm acrosin inhibitor and also functions as a trypsin substrate. It is intended for research use only.
- Potent sperm acrosin inhibitor
- Functions as a trypsin substrate
- For research use only
- Solid storage: 4°C, sealed, away from moisture
- In solvent storage: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
DIASYS DIAGNOSTIC SYSTEMS USA LLC DiaSys Glucose Hexokinase FS is a ready-to-use two component photometric reagent to determine Glucose in serum, heparin plasma or urine on photometric systems. Each set contains R1=800mL, R2=200mL
Diagnostic reagent for quantitative in vitro determination of Glucose in animal serum, heparin plasma or urine on photometric systems. For veterinary or research use only. Glucose concentration is mainly measured in diagnosis and monitoring of diabetes mellitus treatment. Detection of neonatal hypoglycemia, the exclusion of pancreatic islet cell carcinoma as well as the evaluation of carbohydrate metabolism in various diseases represent further applications. Method: Enzymatic UV test using hexokinase. The reagent has a high specificity and wide measuring range (2 to 900 mg/dL) and is formulated according to IFCC/AACC gold standard methodology. Reagent 1 contains TRIS, Mg2+, ATP and NAD, reagent 2 contains Mg2+, Hexokinase and Glucose-6-Phospatedehydrogenase. Reagents must be stored refrigerated.
Medchemexpress LLC Maltitol (standard) | 585-88-6 | 96.15% | 500 MG
Maltitol is an orally active polyol and sugar alcohol sweetener produced by the hydrogenation of maltose. It can replace sucrose and has characteristics of having a minor impact on blood sugar and potential prebiotic effects. This analytical standard is intended for research and analytical applications.
- Analytical standard for research and analytical applications
- Orally active polyol and sugar alcohol sweetener
- Can replace sucrose
- Minor impact on blood sugar
- Potential prebiotic effects
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
Sigma Aldrich Fine Chemicals Biosciences α-Lactose monohydrate 99% total lactose basis (GC) | 5989-81-1 | MFCD00150747 | 1kg
α-Lactose monohydrate 99% total lactose basis (GC) | MW: 360.31 | 5989-81-1 | MFCD00150747 | 1kg
Medchemexpress LLC Lipopolysaccharides, from E. coli O26:B6 | 10-100 kDa | 10 MG
Lipopolysaccharides from Escherichia coli O26:B6 are purified endotoxins used to activate Toll-like receptor 4 and stimulate innate immune responses in vitro and in vivo. They are commonly used to model inflammation, sepsis, and acute lung injury and for testing immune-modulating compounds.
- Purified endotoxin that stimulates TLR4 signaling.
- Suitable for in vitro and in vivo inflammation models.
- White to off-white solid; soluble in water (≈50 mg/mL with sonication).
- Store sealed away from moisture; in solvent store -80°C (6 months) or -20°C (1 month).
- Documentation available: datasheet, COA, SDS, handling instructions.
Medchemexpress LLC (-)-Fucose (Standard) | 2438-80-4 | 164.16 | 50 MG
(-)-Fucose is an analytical standard used in research and analytical applications. It is a hexose that plays a crucial role in various biological processes, including blood group antigen substructure determination, leukocyte-endothelial adhesion, and host-microbe interactions. This compound has demonstrated oral activity and the ability to inhibit CL11-induced inflammatory responses in the kidney, as well as tumor growth.
- Analytical standard for research and analytical applications.
- Classified as a hexose.
- Involved in A and B blood group antigen substructure determination.
- Mediates selectin-mediated leukocyte-endothelial adhesion.
- Participates in host-microbe interactions.
- Orally active.
- Inhibits CL11-induced inflammatory response in kidney.
- Inhibits tumor growth.
Medchemexpress LLC Sucrose (standard) | 57-50-1 | 99.8% | 100 MG
Sucrose (Standard) is the analytical standard of Sucrose. This product is intended for research and analytical applications. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al.
- Grade of analytical standard.
- Reference standard supplied for assay.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC and MS.
eMolecules 2168552-79-0 | 1-METHYLCYCLOBUTANE-1,3-DIOL | AstaTech102.133 | C5H10O2 | 95.000 | CC1(O)CC(O)C1 | 0.1g | 801703731
1-METHYLCYCLOBUTANE-1,3-DIOL | AstaTech | 2168552-79-0102.133 | C5H10O2 | 95.000 | CC1(O)CC(O)C1 | 0.1g | 801703731
Sigma Aldrich Fine Chemicals Biosciences 2 Ntrophenyl beta D cello500MG
2 Ntrophenyl beta D cello500MG
Sigma Aldrich Fine Chemicals Biosciences GenEluteTM Blood Genomic D
The GenElute Blood Genomic DNA kit provides a simple and convenient way to isolate pure genomic DNA from fresh or aged (older than 24 hours) whole blood. The kit combines the advantages of silica binding with a microspin format and eliminates the need for expensive resins alcohol precipitation and hazardous organic compounds such as phenol and chloroform.
Medchemexpress LLC Dodecyl β-D-glucopyranoside | 59122-55-3 | MFCD00063298 | 98.0% | 348.47 | C18H36O6 | 5 G
Dodecyl β-D-glucopyranoside is a non-ionic surfactant used to solubilize and stabilize membrane proteins and membrane-associated complexes in biochemical research. It is supplied as a high-purity, white to off-white solid with specified storage conditions to preserve chemical integrity.
- Non-ionic detergent suitable for membrane protein solubilization.
- High purity: 98.0%.
- Molecular formula C18H36O6 and molecular weight 348.47.
- White to off-white solid appearance.
- Optical rotation: -24.47° (C = 0.01 g/mL, MeOH, 20°C, 589 nm).
- Recommended storage: -20°C sealed; in solvent stability: -80°C for 6 months, -20°C for 1 month.
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Sigma Aldrich Fine Chemicals Biosciences Methyl cellulose | 9004-67-5 | MFCD00081763 | 500g
Methyl cellulose | 9004-67-5 | MFCD00081763 | 500g