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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside is most commonly known as X-Gal. X-gal is a histochemical substrate for β-galactosidase which cleaves X-Gal to yield an insoluble blue precipitate.
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Chemical. CAS 85618-21-9. Formula C14H28O5S. MW 308.4. Non-ionic detergent. For functional solubilization, purification and crystallography of membrane proteins. The thioether linkage makes it resistant to degradation by beta-glucosidase enzymes. For the stabilization and activation of enzymes. Used for cell lysis experiments.
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Complement factor D-IN-2 is an inhibitor of complement factor D. It targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. This compound can be used for the research of autoimmune diseases by reducing the excessive activation of complement factor D.
Inhibits complement cascade at an early stage
Reduces excessive activation of complement factor D
Useful for research into autoimmune diseases
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The primary attribute of DDM is its capability to extract hydrophobic proteins while maintaining the solution-phase protein conformation DDM also allows the protein to be reformed following denaturization Most membrane-bound proteins are -helix bundles which are less robust to changes in their cellular environment DDM offers a detergent capable of preserving these proteins This is in contrast to other harsher ionic detergents that destabilize and permanently denature -helical membrane-bound proteins DDM has been used to solubilize the multidrug-transporter protein EmrE as well as the nucleoside-specific porin protein Tsx
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Trehalose-6,6'-dibehenate is an orally active glycolipid that activates Mincle and inflammasome, inducing IL-1β secretion in a caspase activity-dependent manner. This compound also exerts a Myd88-dependent adjuvant activity.
Orally active glycolipid
Activates Mincle and inflammasome
Induces IL-1β secretion in a caspase activity-dependent manner
Exerts Myd88-dependent adjuvant activity
Induces Th-1/Th-17 immune responses
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Sucrose octasulfate sodium is a derivative of sulfated oligosaccharides that acts as a matrix metalloproteinase (MMP) inhibitor. It stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach by directly affecting D cells in the gastric mucosa, contributing to its ulcer-healing effect. It can also be used as a pharmaceutical excipient and has shown to improve wound closure in diabetic foot ulcers and venous leg ulcers.
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D-glyceric acid sodium is the monosodium salt of D-glyceric acid, an endogenous metabolite supplied as a research-grade reagent for biochemical and metabolomics studies. It is commonly used in investigations of metabolic disorders and analytical method development where a characterized standard is required.
High purity (99.0%) suitable for analytical and research applications.
Monosodium salt form increases solubility in aqueous solutions.
Relevant for research into metabolic disorders such as primary hyperoxaluria type I and glutaric acidemia type II.
Solid, white to off-white powder that is stable under recommended storage conditions.
Available in small laboratory pack sizes for convenient use in assay development.
Documentation available including datasheet, certificate of analysis, and safety data sheet.
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Galactose 1-phosphate is an intermediate in galactose metabolism and nucleotide sugars. This product is provided as a potassium salt, which typically offers enhanced water solubility and stability, and is intended for research use only.
Intermediate in galactose metabolism and nucleotide sugars
Enhanced water solubility
Enhanced stability
For research use only
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D-( )-Trehalose-13C12 is a 13C isotope labeled version of D-( )-Trehalose (HY-N1132) D-( )-Trehalose which is widespread can be used as a food ingredient and pharmaceutical excipient[1]
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ISRIB (trans-isomer) (CAS 1597403-47-8) is a small molecule inhibitor of the integrated stress response (ISR) ISR activation involves the phosphorylation of eukaryotic initiation factor 2 (eIF2 ) by stress-sensitive kinases leading to reduced global protein synthesis and enhanced translation of select mRNAs ISRIB counteracts ISR signaling by reversing the translational suppression induced by phosphorylated eIF2 inhibiting production of ATF4 protein decreasing stress granule assembly and promoting polyribosome formation during endoplasmic reticulum (ER) stress ISRIB stabilizes and activates eIF2B by facilitating its dimerization Rodent studies demonstrate ISRIB s capacity to enhance hippocampal-dependent spatial and fear-related learning and memory highlighting its utility in neuroscience research
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VEGF-D a growth factor stimulates proliferation migration and vessel permeability It is crucial for vascular development and maintenance of lymphatic endothelium VEGF-D binds and activates VEGFR-3 initiating essential signaling pathways Structurally it forms a non-covalent homodimer playing an intricate role in vascular processes VEGF-D Protein Rat (HEK293 Fc) is the recombinant rat-derived VEGF-D protein expressed by HEK293 with N-hFc labeled tag
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Cathepsin D Protein Mouse (HEK293 His) is an approximately 56 0 kDa mouse cathepsin D with a His tag Cathepsin D is a lysosomal aspartic protease of the pepsin family[1]
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D-Galactose pentaacetate inhibits leucine-induced insulin release D-Galactose pentaacetate can be used for the research of persistent hyperinsulinemia in childhood or insulinoma[1][2]
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