Glycerol kinase, microorganism (GyK) is an NR4A1 inhibitor with enzymatic activity. It binds to and inhibits the transcription factor NR4A1, regulating hepatic gluconeogenesis and reducing blood glucose. It also promotes thermogenesis and modulates fatty acid composition, showing potential for improving glucose homeostasis in diabetic models. This product is suitable for studies on diabetes and obesity.
- Inhibits NR4A1 transcription factor
- Regulates hepatic gluconeogenesis
- Reduces blood glucose levels
- Promotes white adipose tissue browning and thermogenesis
- Modulates fatty acid composition and energy metabolism
- Effective in antagonizing hyperglycemia in diabetic mouse models
- Used for diabetes and obesity studies
- Appearance: White to off-white solid
- Solubility: ≥ 50 mg/mL in H2O
- Specific activity: >180 U/mg protein
- Sourced from microorganism