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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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Diethylstilbestrol-d3 is deuterium labeled Diethylstilbestrol. It is for research use only and can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during drug development.
Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
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T-bet-TAR-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
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4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium is a fluorogenic enzymatic substrate used to measure iduronate-2-sulfatase (I2S) activity. Enzymatic hydrolysis releases the fluorescent reporter 4-methylumbelliferone (4-MU), enabling quantitative fluorescence-based assays used in lysosomal storage disease research, including screening and diagnostic applications for disorders such as Hurler syndrome. Supplied as a sodium salt powder.
Fluorogenic substrate for iduronate-2-sulfatase (I2S) assays.
Releases 4-methylumbelliferone (4-MU) upon hydrolysis for fluorescence detection.
Suitable for quantitative enzyme activity and diagnostic research applications.
Provided as a sodium salt powder for storage and handling convenience.
CAS number 2181774-46-7; molecular weight 476.32; formula C16H14Na2O12S.
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PROTAC BET Degrader-1 is a proteolysis-targeting chimera (PROTAC) that links Cereblon and BET ligands to promote ubiquitin-mediated degradation of BET family proteins BRD2, BRD3, and BRD4 at low concentrations. It is supplied for research use in studies of BET protein biology and targeted protein degradation.
Induces degradation of BRD2, BRD3, and BRD4 at low nanomolar concentrations.
High purity (99.4%) suitable for biochemical and cell-based assays.
Available as solid or as DMSO solution for experimental flexibility.
High solubility in DMSO (≥ 50 mg/mL) for convenient dosing.
Stable when stored per manufacturer recommendations for long-term experiments.
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ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
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