Carbohydrates
Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 1 ML
K-Ras ligand-Linker Conjugate 4 incorporates a ligand for the K-Ras recruiting moiety and a PROTAC linker, designed to recruit E3 ligases such as VHL, CRBN, MDM2, and IAP. This conjugate is utilized in the synthesis of potent PROTAC K-Ras Degrader-1, which has demonstrated ≥70% degradation efficacy in SW1573 cells. PROTACs function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- Incorporates a ligand for a K-Ras recruiting moiety
- Includes a PROTAC linker to recruit E3 ligases (VHL, CRBN, MDM2, IAP)
- Used in the synthesis of a potent PROTAC K-Ras degrader
- Demonstrates high degradation efficacy in SW1573 cells
- Utilizes the intracellular ubiquitin-proteasome system for selective protein degradation
Medchemexpress LLC Guanosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, sodium salt (1:1) | 51116-00-8 | 99.7% | 50 MG
Dibutyryl-cGMP sodium (Bt2cGMP sodium) is a cell-permeable cGMP analogue that preferentially activates cGMP-dependent protein kinase (PKG). It inhibits the release of [3H]-arachidonic acid from γ thrombin-stimulated human platelets and induces peripheral antinociception via activation of ATP-sensitive K+ channels. It is for research use only and not sold to patients.
- Appearance: solid
- Color: white to light yellow
- Molecular weight: 507.37
- Formula: C18H23N5NaO9P
- Solubility in H2O: 100 mg/mL (197.09 mM; requires ultrasonic)
- Solubility in DMSO: 100 mg/mL (197.09 mM; requires ultrasonic; hygroscopic DMSO has a significant impact on solubility)
Teknova 50mg/mL Streptomycin Solution. 25mL, Sterile.
Premade antibiotic solutions are ready-to-use as a supplement for your tissue culture, bacteria media or other specific needs. Antibiotics are often used in cell culture to prevent contamination, maintain aseptic conditions, or select for cells containing genetic modifications.
Chem-Impex International, Inc. N4-Benzoylcytidine | MFCD00010572 | 5G
N4-Benzoylcytidine, MFCD00010572, 5G
Medchemexpress LLC L-mannose | 10030-80-5 | MFCD00063884 | 98.0% | 180.16 g/mol | C6H12O6 | 100 MG
L-mannose is a naturally occurring monosaccharide supplied as a solid reagent for laboratory research. It is used as a biochemical substrate and in enzyme assays, notably as a substrate for mannose-6-phosphate isomerase, and is suitable for metabolic and analytical studies. The compound has a molecular weight of 180.16 g/mol and is commonly provided at about 98% purity.
- Naturally occurring monosaccharide reagent
- High purity (≈98.0%) suitable for research use
- Molecular weight 180.16 g/mol; formula C6H12O6
- Supplied as a solid for ease of handling
- Useful as a substrate for mannose-6-phosphate isomerase and enzyme assays
- Suitable for biochemical and metabolic studies
Medchemexpress LLC L-(+)-arabinose | 5328-37-0 | MFCD00135866 | 100.0% | 150.13 g/mol | C5H10O5 | 100 MG
L-(+)-Arabinose is a high-purity analytical reference standard (CAS 5328-37-0) used for qualitative and quantitative analyses in chromatography and mass spectrometry. Provided as a white to off-white solid with molecular weight 150.13 g/mol, it is intended for research and analytical applications; store under conditions specified in the certificate of analysis.
- High purity suitable for analytical applications.
- Compatible with HPLC, GC, and MS methods.
- White to off-white solid form for easy handling.
- Accurate molecular weight and formula for reference use.
- Available in small packaged sizes for method development.
Medchemexpress LLC α-D-mannose pentaacetate | 4163-65-9 | MFCD00069798 | 97.0% | 390.34 g/mol | C16H22O11 | 25 G
α-D-Mannose pentaacetate is an acetylated derivative of D-mannose used as a biochemical reagent and building block in carbohydrate chemistry. It is suitable for glycosylation studies and other life-science research that require protected sugar derivatives.
- Acetylated D-mannose derivative for glycosylation and synthesis studies.
- High purity: 97.0%.
- Physical form: solid, white to off-white.
- Molecular formula C16H22O11; molecular weight 390.34 g/mol.
- Storage: powder at -20°C (3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available pack sizes: 25 g, 50 g, 100 g, bulk on inquiry.
Medchemexpress LLC HA/Hemagglutinin H1 20ug
HA/Hemagglutinin Protein is a viral surface glycoprotein that mediates virus adsorption to host cells and promotes membrane fusion required for infection HA/Hemagglutinin Protein plays a key role in the process of viral infection of host cells HA/Hemagglutinin Protein H1N1 (Biotinylated ACP41953 1 HEK293 His) is a recombinant HA/Hemagglutinin protein expressed by HEK293 and carrying a C-His tag[1][2]
Medchemexpress LLC D-ribose (mixture of isomers) | 50-69-1 | MFCD00135453 | 98.0% | 150.13 g/mol | C5H10O5 | 1 G
D-Ribose (mixture of isomers) is a naturally occurring pentose sugar supplied as a white crystalline powder for research use. It functions as an energy metabolite and enzyme substrate and is commonly used in studies of nucleotide synthesis, metabolic pathways, and protein glycation.
- High purity (98.0% by NMR).
- Molecular weight 150.13 g/mol; chemical formula C5H10O5.
- Suitable as an enzyme substrate and metabolite in biochemical assays.
- White crystalline powder with good water solubility.
- Provided in laboratory-scale pack sizes for research applications.
Thermo Scientific Production Chemicals and Services DEXTRS ANHY USP/EP/BP/JP 12KG
NC3888231 DEXTRS ANHY USP/EP/BP/JP 12KG
Sigma Aldrich Fine Chemicals Biosciences N-Acetylneuraminic acid synthetic, >=95% | 131-48-6 | MFCD00006620 | 100MG
N-Acetylneuraminic acid synthetic, >=95% | Purity: >=95% | Mol Wt: 309.27 | 131-48-6 | MFCD00006620 | 100MG
Medchemexpress LLC Cuda disodium | 98.0% | 386.48 g/mol | C19H36N2Na2O3 | 5 MG
CUDA disodium is a potent, research-use small molecule inhibitor of soluble epoxide hydrolase (sEH) that modulates PPARα activity. Reported IC50 values are 11.1 nM (mouse sEH) and 112 nM (human sEH). Supplied as a 5 mg sample with 98.0% purity, it is intended for biochemical and pharmacological research in lipid metabolism and cardiovascular disease models.
- Potent sEH inhibition with reported IC50s of 11.1 nM (mouse) and 112 nM (human).
- Enhances peroxisome proliferator-activated receptor alpha activity in cellular models.
- High purity (98.0%) suitable for biochemical assays.
- Small quantity packaging (5 mg) for screening and early-stage studies.
- Storage recommendations provided for stability in solvent and dry conditions.
Medchemexpress LLC ERRα Ligand-Linker Conjugates 1 | 98.8% | 100 MG
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα) and a PROTAC linker, which recruits E3 ligases MDM2. This product can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1, which is an ERRα degrader.
- Incorporates a ligand for estrogen-related receptor alpha (ERRα) and a PROTAC linker.
- Recruits E3 ligases MDM2.
- Utilized in the synthesis of a series of PROTACs.
- Appears as a light yellow to yellow solid.
- Recommended storage at -20°C under nitrogen, away from moisture.
- High solubility in DMSO (200 mg/mL) with sonication.
Sigma Aldrich Fine Chemicals Biosciences N-Acetylneuraminic acid synthetic, >=95% | 131-48-6 | MFCD00006620 | 25MG
N-Acetylneuraminic acid synthetic, >=95% | Purity: >=95% | Mol Wt: 309.27 | 131-48-6 | MFCD00006620 | 25MG