The TGF beta Receptor II Antibody is a Rabbit-derived, non-conjugated IgG polyclonal antibody designed to target TGF beta Receptor II. This transmembrane protein is crucial for binding TGF-beta, forming a complex that phosphorylates proteins to regulate gene transcription. It plays a significant role in cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumor genesis. Mutations in the associated gene have been linked to various health conditions including Marfan Syndrome and Loeys-Deitz Aortic Aneurysm Syndrome.
- Rabbit-derived polyclonal antibody
- Non-conjugated IgG isotype
- Targets TGF beta Receptor II
- Reactive with human, mouse, and rat samples
- Applications include WB, ELISA, IHC-P, and ICC/IF
- Formulated in PBS with 50% glycerol, 0.5% BSA, and 0.02% sodium azide
- Stable for 1 year at -20°C; avoid freeze/thaw cycles
- Affinity purified