Inosine-13C5 is the 13C5 labeled version of Inosine. Inosine is a naturally occurring purine nucleoside produced from adenosine catabolism. It exhibits anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective effects, acting as an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
- Stable heavy isotopes like carbon-13 are incorporated into drug molecules as tracers for quantitation in drug development.
- Dose-dependently stimulates cAMP production through A2AR.
- Dose-dependently induces hA2AR-mediated ERK1/2 phosphorylation.
- Reduces oxidative stress in MES 23.5 cells cultured with astrocytes at 100 μM for 24 hours.