Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. They possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. They can be widely used to induce cellular inflammation and establish animal models related to inflammation.
- Endotoxins and TLR4 activators
- Extracted from Escherichia coli (E. coli O55:B5)
- Classified as S (smooth) type LPS
- Possess typical three-part structure: O-antigen, core oligosaccharide, and lipid A
- Activate TLR-4 in immune cells
- Exhibit high pyrogenicity
- Demonstrate dose and serotype specificity