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Hydroxyprogesterone caproate (CAS No 630-56-8) is a synthetic progestin used in biomedical research primarily within the fields of endocrinology and obstetrics Originating from modifications of naturally occurring progesterone this compound acts by binding to progesterone receptors influencing the regulation of menstrual cycles and maintaining pregnancy Its mechanism of action involves modulating hormonal pathways crucial for gestational support In vitro studies commonly report activity in the nanomolar to low micromolar range indicating its potent receptor affinity Typical research applications include various cell models and animal studies to investigate reproductive health with drug screening processes benefiting from its predictable biological activity Experimental concentrations typically depend on the specific research design
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Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Diflucortolone valerate (Diflucortolone 21-valerate) is a corticosteroid esterified with valeric acid. It helps to reduce itching redness and swelling. purity: 98%
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Ethyl linoleate (Linoleic Acid ethyl ester) is an orally active unsaturated fatty acid. It inhibits the Akt/GSK3β/β-catenin signaling pathway and the activation of NF-κB. This compound induces heme oxygenase-1 and inhibits tyrosinase, leading to whitening and anti-inflammatory effects. Ethyl linoleate also promotes compound absorption and significantly influences atherosclerosis. It is used in the research of inflammatory diseases and can be utilized in cosmetics.
Orally active unsaturated fatty acid.
Inhibits the Akt/GSK3β/β-catenin signaling pathway and NF-κB activation.
Induces heme oxygenase-1.
Inhibits tyrosinase.
Possesses whitening and anti-inflammatory effects.
Promotes compound absorption.
Has a significant influence on atherosclerosis.
Used in research of inflammatory diseases.
Can be used in cosmetics.
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A hydroxy fatty acid; a partial agonist of FFAR1/GPR40 and GPR85 receptors in vitro (EC50s = 6.7 and 12.8 μM, respectively); inhibits bovine hepatic ligase (Ki = 4.4 μM); inhibits medium-chain acyl-CoA synthetase by 48% in mouse kidney mitochondria (40 μM)
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