Lipids and Lipid Derivatives
Medchemexpress LLC CQ-Lyso | 2089438-23-1 | 98.95% | 485.62 | 100 MG
CQ-Lyso is a lysosome-targeting chromenoquinoline. It is a fluorescent probe designed for measuring the pH of lysosomes in living cells using single-wavelength excitation, and it can visualize dynamic pH changes within lysosomes.
- Lysosome-targeting chromenoquinoline
- Fluorescent probe for measuring lysosomal pH in living cells
- Uses single-wavelength excitation
- Visualizes dynamic pH changes within lysosomes
Cambridge Isotope Laboratories Lyso-PC 24 0 (unlabeled) CP 95% 5 mg
Lyso-PC 24 0 (unlabeled) CP 95% 5 mg
Cayman Chemical C8 CeramIde-1-phosphated1825mg
C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C8 ceramide-1-phosphate are essentially the opposite of C8 ceramide; it induces DNA synthesis and cell division. The effects of C8 ceramide-1-phosphate can be attenuated by simultaneous treatment with C2 or C8 ceramide.{5183}
Medchemexpress LLC C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) | 74713-59-0 | 98.0% | 425.69 | 1 G
C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. It exhibits anti-proliferation properties and functions as a potent chemotherapeutic agent. It stimulates dendritic cells to promote T cell responses during virus infections and induces slight activation of protein kinase (PKC) in vitro.
- Cell-permeable analog of ceramides
- Anti-proliferation and chemotherapeutic agent
- Stimulates dendritic cells for T cell responses
- Activates protein kinase C
- Reduces tumor-cell proliferation
- Induces necrosis-like cell death
- Increases ROS levels
- Triggers apoptosis and G1 arrest in NSCLC H1299 cells
- Enhances CD8+ and CD4+ T cell responses in viral infections
Medchemexpress LLC C16 ceramide-1-phosphate (d18:1/16:0) (ammonium) | 1246303-22-9 | 98% | C34H71N2O6P | 500 UG
C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium) is an ester product used as a laboratory chemical and for the manufacture of substances.
- Appears as a solid
- Stable under recommended storage conditions
- Store at -20°C, protect from light, and under nitrogen
- Suitable for laboratory use
Medchemexpress LLC DMTr-2'-O-C22-rC-3'-CE-Phosphoramidite | 2923115-93-7 | 98.0% | 1096.42 | 1 ML
DMTr-2'-O-C22-rC-3'-CE-Phosphoramidite (Compound 114) is a phosphoramidite that can be used for the synthesis of oligonucleotides. It is for research use only and not sold to patients.
- Used for the synthesis of oligonucleotide.
- For research use only.
Medchemexpress LLC 24:0 Lyso PC-13C6 | 2483735-01-7 | 97.5% | 613.80 | 1 MG
24:0 Lyso PC-13C6 is the 13C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP) that could be used for mRNA drug delivery. It can also be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Lysophosphatidylcholine (15:0) | 108273-89-8 | MFCD00674356 | 99.6% | 481.60 | C23H48NO7P | 5 MG
15:0 Lyso PC is a lysophosphatidylcholine used as an analytical lipid standard and research reagent for studies of membrane remodeling, inflammatory signaling, and lipid biomarkers in cardiovascular disease. It is supplied as a solid with high purity suitable for analytical and biochemical applications.
- High purity (99.6%) for reproducible analytical results.
- Molecular weight 481.60 and formula C23H48NO7P for precise identification.
- White to off-white solid appearance for easy handling.
- Available in small mg-scale amounts suitable for research use.
- Stable as a powder at -20°C for long-term storage.
Medchemexpress LLC 1,3-octadecanediol, 2-amino-, (2S,3R)- | 764-22-7 | MFCD07371371 | 99.6% | 301.51 g/mol | C18H39NO2 | 50 MG
D-Erythro-dihydrosphingosine is a sphingoid base (sphinganine) that directly inhibits cytosolic phospholipase A2α (cPLA2α). Supplied as a white to off-white solid for research use, it has molecular formula C18H39NO2, molecular weight 301.51 g/mol, and CAS 764-22-7. The Certificate of Analysis reports an LCMS purity of 99.55% and recommends sealed storage at -20°C (in solvent: -80°C up to 6 months).
- Direct inhibitor of cPLA2α for mechanistic studies.
- High purity (99.55%) for reproducible results.
- Well-characterized chemical identity (C18H39NO2; MW 301.51 g/mol).
- Solid, white to off-white appearance for easy handling.
- Recommended storage conditions to maintain compound integrity.
Medchemexpress LLC C6 ceramide | 124753-97-5 | 99.8% | 397.63 | 5 MG
C6 Ceramide (C6-Cer), also known as N-Hexanoylsphingosine, is a short-chain, cell-permeable ceramide pathway activator. It exhibits anticancer activity by promoting miR-29b expression, suppressing endothelial cell proliferation, migration, and angiogenesis via the Akt signal pathway. C6 Ceramide also induces cell cycle arrest, apoptosis, inhibits tumor growth, and enhances chemotherapy effects, serving as an adjuvant for chemotherapeutic agents.
- Short-chain, cell-permeable ceramide pathway activator
- Anticancer activity
- Promotes miR-29b expression
- Suppresses proliferation, migration, and angiogenesis of endothelial cells by targeting the Akt signal pathway
- Induces cell cycle arrest and apoptosis
- Inhibits tumor growth
- Enhances the effects of chemotherapy in drug-resistant cancer cells
- Can be used as an adjuvant for chemotherapeutic agents
Medchemexpress LLC 7-(4-(2-((1,3-Dihydroxyoctadec-4-en-2-yl)amino)-2-oxoethoxy)phenyl)-5,5-difluoro-3-(thiophen-2-yl)-5 | 571186-05-5 | 99.17% | 705.70 | 250 UG
The Golgi apparatus consists of flattened vesicles stacked together, which are round with expanded and perforated edges. BODIPY TR Ceramide is a BODIPY-labeled ceramide derivative that functions as a Golgi-specific fluorescent dye. It is synthesized in the endoplasmic reticulum and subsequently transported to the Golgi apparatus through ceramide transport protein (CERT) or vesicular translocation, enabling specific labeling. This dye allows for the visualization of individual cells with an excitation/emission (Ex/Em) of 589 nm/616 nm.
- Golgi-specific fluorescent dye
- Can visualize individual cells
- Excitation/emission (Ex/Em) = 589 nm/616 nm
Medchemexpress LLC 17:1 lyso pc | 1246304-62-0 | 98.0% | 507.64 | C25H50NO7P | 10 MG
17:1 Lyso PC is a lysophosphatidylcholine lipid used to simulate biological phospholipid membranes and to formulate liposomes for drug delivery research. It forms vesicles with concentric phospholipid bilayers, enabling encapsulation of polar, water-soluble payloads in the internal aqueous space and incorporation of lipophilic payloads within the lipid layer. It is commonly used in studies of anticancer, anti-infection, and nucleic-acid delivery.
- Molecular formula: C25H50NO7P.
- Molecular weight: 507.64.
- Purity: 98.0%.
- CAS number: 1246304-62-0.
- Appearance: white to off-white solid-liquid mixture.
- Storage: -20°C (pure form, long term); -80°C (in solvent, short term).
- Pack size: 10 mg.
- Typical applications: liposome formulation and nucleic-acid delivery research.
Medchemexpress LLC C16 PEG2000 Ceramide | 212116-78-4 | 99.4% | (C2H4O)nC39H73NO6 | 50 MG
C16 PEG2000 Ceramide is a polyethylene glycolylated ceramide that functions as a lipid carrier for delivery. It induces autophagy and is suitable for cancer research.
- Functions as a lipid carrier for delivery
- Induces autophagy
- Suitable for cancer research
- Exhibits cytotoxicity in N2a cells
- Promotes autophagy in N2a cells
- Increases LC3-II/LC3-I ratios in N2a cells
- Reduces WT-Tau and P301L-Tau proteins in N2a cells
Medchemexpress LLC Cq-lyso | 2089438-23-1 | 99.0% | 485.62 | C30H35N3O3 | 10 MG
CQ-Lyso is a lysosome-targeting chromenoquinoline fluorescent probe used to measure lysosomal pH in living cells with single-wavelength excitation. It enables visualization of dynamic pH changes in lysosomes and is supplied for research use only.
- Lysosome-targeting chromenoquinoline fluorescent probe.
- Measures lysosomal pH using single-wavelength excitation.
- Enables visualization of dynamic pH changes in living cells.
- High purity for reliable experimental results.
- Soluble in DMSO and DMF at up to 100 mg/mL with warming and sonication.
- Store solid at 4°C and protect from light; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Available in small research pack quantities (e.g., 10 mg).
Medchemexpress LLC Polyoxyl 40 stearate | 171286-89-8 | 98.0% | 2046.58 | C98H196O42 | 5 G
Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant and pharmaceutical excipient used to improve solubility, stability, and processability of drug formulations. It functions as an emulsifying agent and solubilizer for hydrophobic active ingredients across topical, oral, and parenteral preparations.
- Nonionic surfactant and emulsifier.
- Improves solubility of hydrophobic compounds.
- Enhances formulation stability and processability.
- Suitable for topical, oral, and parenteral applications.
- High apparent purity (98.0%).
- Available in small research quantities (1 g-50 g).