Lipids and Lipid Derivatives
Cayman Chemical 2-hexyl-4-Pentynoic Acid, Purity: ≥95%, CAS: 96017-59-3, 5 g
Inhibits HDAC activity much more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM); induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM; induces the expression of Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity
Selleck Chemical LLC Daminozide S4800-500mg
Daminozide (Aminozide DMASA DIMG B 995 Alar Kylar B-NINE SADH) a plant growth regulator selectively inhibits the KDM2/7 JmjC subfamily with IC50 of 1 5 0 7 M for KDM2A It is at least 100-fold selective as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members tested with IC50s of 2 M or less against KDM2A PHF8 and KIAA1718 and IC50s of 127 M for KDM3A or greater (mM range) against other demethylases
Cayman Chemical 2-hexyl-4-Pentynoic Acid, Purity: ≥95%, CAS: 96017-59-3, 250 mg
Inhibits HDAC activity much more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM); induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM; induces the expression of Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity
eMolecules 6089-09-4 | Pent-4-ynoic Acid | AA Blocks LLC | MFCD00004407 | 98.101 | C5H6O2 | 0.000 | OC(=O)CCC#C | 1g | 410168581
Pent-4-ynoic Acid | AA Blocks LLC | 6089-09-4 | MFCD00004407 | 98.101 | C5H6O2 | 0.000 | OC(=O)CCC#C | 1g | 410168581
Medchemexpress LLC Angelic acid | 565-63-9 | MFCD00002654 | 5 MG
Angelic acid is a ferroptosis inducer that targets NRF2 degradation. It binds to the NRF2 protein, promoting its degradation through the ubiquitination-proteasome pathway. This action mitigates the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation, leading to the induction of ferroptosis in tumor cells.
- Purity: 99.20%
- Molecular weight: 100.12
- Molecular formula: C5H8O2
- Appears as a white to off-white solid
- Enhances accumulation of intracellular reactive oxygen species
- Upregulates ferroptosis-related markers such as CHAC1 and PTGS2
- Synergizes with other ferroptosis inducers to boost anti-tumor effects
- Scavenges UVA-induced reactive oxygen species
- Inhibits skin fibroblast senescence and prevents extracellular matrix degradation
- Contributes to wound healing and has sedative activity
Medchemexpress LLC Fumaric acid | 110-17-8 | MFCD00002700 | 99.9% | 116.07 | C4H4O4 | 500 G
Fumaric acid is an organic dicarboxylic acid and endogenous metabolite supplied as a research-grade reagent for laboratory studies. It is used in metabolic and signaling pathway research and includes specified purity, identity, and storage information; for research use only.
- Research-grade purity (99.9%) for analytical and biochemical applications.
- Chemical identity confirmed: CAS 110-17-8, formula C4H4O4, MW 116.07.
- Available as a solid in multiple package sizes up to 500 g.
- Forms clear solutions in common buffers for assay preparation.
- Defined storage conditions extend stability in solid and solution forms.
- Intended for research use only.
Cayman Chemical cis-2-Decenoic Acid, Purity: ≥95%, CAS: 15790-91-7, 50 mg
An unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a dispersion response in biofilms formed by gram-negative and gram-positive bacteria, as well as by the yeast C. albicans; promotes dispersion of P. aeruginosa biofilms over a concentration range of 1.0 to 10 nM
Selleck Chemical LLC Monomethyl glutarate
Monomethyl glutaric acid (5-Methoxy-5-oxopentanoic acid) is a dicarboxylic acid monoester and has a role as a human urinary metabolite
eMolecules 142-45-0 | ACETYLENEDICARBOXYLIC ACID | Broadpharm | MFCD00004362 | 114.056 | C4H2O4 | 99.000 | OC(=O)C#CC(O)=O | 1g | 200622478
ACETYLENEDICARBOXYLIC ACID | Broadpharm | 142-45-0 | MFCD00004362 | 114.056 | C4H2O4 | 99.000 | OC(=O)C#CC(O)=O | 1g | 200622478
Cayman Chemical trans-2-Decenoic Acid, Purity: ≥95%, CAS: 334-49-6, 25 g
An unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees; isolated in conjunction with 10-HDA (Item No. 10976) and both demonstrate weak estrogenic activity, inhibiting binding of 17β-estradiol (Item No. ISO60155) to estrogen receptor β